MỐI LIÊN QUAN CỦA THANG ĐIỂM NUTRIC SỬA ĐỔI (MNUTRIC) VÀ KẾT CỤC LÂM SÀNG Ở BỆNH NHÂN SỐC NHIỄM KHUẨN

Abstract

Introduction: Patients with septic shock face multiple risks, including nutritional challenges. Currently, there is a lack of easily applicable nutritional screening tools in clinical practice for assessing patients with sepsis and septic shock. Objective: To investigate the association between nutritional risk, as assessed by the mNUTRIC score and clinical outcomes in patients with septic shock. Methods and Subjects: A cross-sectional study was conducted on 151 patients with septic shock admitted to the Intensive Care Unit of Hoan My Cuu Long Hospital from January 2023 to December 2024. Results: High nutritional risk was observed in 61.6% of patients. Patients with high nutritional risk had higher rates of neurological dysfunction (76.3%), renal dysfunction (74.2%), thrombocytopenia (49.5%), respiratory failure (90.3%), and refractory shock (39.8%). The 30-day mortality rate was significantly higher in the high-risk group (58.1%) compared to the low-risk group (13.8%), with an adjusted HR=2.56 (95% CI: 1.05–6.25, p=0.039). Additionally, the need for renal replacement therapy, mechanical ventilation, and in-hospital mortality were also higher in patients with mNUTRIC scores ≥5. The mNUTRIC score predicted mortality with AUC=0.74 (95% CI: 0.67–0.82, p<0.001). Conclusion: Patients with high nutritional risk were associated with increased rates of organ dysfunction and higher 30-day mortality. The mNUTRIC score is fairly predictive of 30-day mortality in patients with septic shock.