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Date Published: 23/12/2021
Abstract Views: 184
Views PDF: 249
DOI: https://doi.org/10.51298/vmj.v507i2.1435
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Vol. 507 No. 2 (2021)
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Các bài báo
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Thị Phương Anh, N. ., & Hùng Kiên, Đỗ . (2021). EFFICACY OF GEMCITABINE –CISPLATIN IN METASTATIC NASOPHARYNGEAL CANCER PATIENTS IN VIETNAM NATIONAL CANCER HOSPITAL. Vietnam Medical Journal, 507(2). https://doi.org/10.51298/vmj.v507i2.1435

EFFICACY OF GEMCITABINE –CISPLATIN IN METASTATIC NASOPHARYNGEAL CANCER PATIENTS IN VIETNAM NATIONAL CANCER HOSPITAL

Nguyễn Thị Phương Anh1,, Đỗ Hùng Kiên2
1 Hanoi Medical University
2 Tân Triều Brach of National Cancer Hospital

Main Article Content

Abstract

Objectives: The aims of our study were to investigate the activity and toxicity of gemcitabine – cisplatin regimen in metastatic nasopharyngeal cancer patients. Patients and Methods: Clinical trial, retrospective study. From January 2018 to July 2021, we enrolled 33 metastatic nasopharyngeal cancer patientsin Vietnam National Cancer Hospital. All patients received combination of gemcitabine and cisplatin. Tumor response rateand toxicitys were determined.  Results: Response rate: Overal response rate was 83,9%. Median progression free survival was 8,9 months. Toxicity: Most adverse events were manageable and tolerable. The most common was neutropenia (60.6%), anaemia (90.9%), vomiting and nausea (51.5%), most of them were grade 1 and grade 2. Conclusion: Gemcitabine – cisplatin regimen in metastatic nasopharyngeal cancer patients is high repsond rate and tolerable.

Article Details

Keywords

Nasopharyngeal cancer, recurrent, metastatic stages

References

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