CLINICAL AND MAGNETIC RESONANCE IMAGING FEATURES OF PEDIATRIC OPTIC NEURITIS

Đào Thị Việt Hường1,, Đỗ Thanh Hương1, Cao Vũ Hùng2
1 Hanoi Medical University
2 Vietnam National Children's Hospital

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Abstract

Objectives: Clinical and magnetic resonance imaging features of pediatric optic neuritis. Method: This is a cross-sectional study including 47 patients with optic neuritis in the Neurology Centre of National Children’s Hospital, for a period of 5 years from June, 1th, 2016 to May, 31th, 2021. Results: 47 patients with 83 affected eyes. Mean age of onset was 8,52 ± 3,1. There were 27 male patients and 20 female patients. Male/ female ratio was 1,35/1. 11 patients (23,4%) had unilateral involvement, and 36 patients (76,6%) had bilateral involvement. All patients admitted to the hospital because of reduced or lost vision, 22 patients (46,8%) had viral prodrome during one month before the onset of disease. 68 eyes (81,9%) had a visual acuity lower of 1/10 at the time of initial presentation, 48 eyes (44,9%) had optic disc edema. 9/47 patients (19,1%) had relapse optic neuritis. Magnetic resonance imaging (MRI) brain - orbital showed 10 patients with typical retrobulbar neuritis. In addition, 4 other patients had white/ gray matter lesions from the initial onset, and one patient in this group had a second episode of relapse optic neuritis. Conclusion: Pediatric optic neuritis had poor vision at onset. MRI brain - obital plays an important role in diagnosis and prognosis of disease progression.

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References

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