CLINICAL AND MAGNETIC RESONANCE IMAGING FEATURES OF PEDIATRIC OPTIC NEURITIS
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Abstract
Objectives: Clinical and magnetic resonance imaging features of pediatric optic neuritis. Method: This is a cross-sectional study including 47 patients with optic neuritis in the Neurology Centre of National Children’s Hospital, for a period of 5 years from June, 1th, 2016 to May, 31th, 2021. Results: 47 patients with 83 affected eyes. Mean age of onset was 8,52 ± 3,1. There were 27 male patients and 20 female patients. Male/ female ratio was 1,35/1. 11 patients (23,4%) had unilateral involvement, and 36 patients (76,6%) had bilateral involvement. All patients admitted to the hospital because of reduced or lost vision, 22 patients (46,8%) had viral prodrome during one month before the onset of disease. 68 eyes (81,9%) had a visual acuity lower of 1/10 at the time of initial presentation, 48 eyes (44,9%) had optic disc edema. 9/47 patients (19,1%) had relapse optic neuritis. Magnetic resonance imaging (MRI) brain - orbital showed 10 patients with typical retrobulbar neuritis. In addition, 4 other patients had white/ gray matter lesions from the initial onset, and one patient in this group had a second episode of relapse optic neuritis. Conclusion: Pediatric optic neuritis had poor vision at onset. MRI brain - obital plays an important role in diagnosis and prognosis of disease progression.
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Keywords
pediatric optic neuritis, MRI brain – obital
References
2. Lehman S.S. and Lavrich J.B. (2018). Pediatric optic neuritis. Curr Opin Ophthalmol, 29(5), 419–422.
3. Wilejto M., Shroff M., Buncic J.R., et al. (2006). The clinical features, MRI findings, and outcome of optic neuritis in children. Neurology, 67(2), 258–262.
4. Averseng-Peaureaux D., Mizzi M., Colineaux H., et al. (2018). Paediatric optic neuritis: factors leading to unfavourable outcome and relapses. Br J Ophthalmol, 102(6), 808–813.
5. Lê Thị Doan (2013). Nghiên cứu một số đặc điểm lâm sàng và kết quả điều trị bệnh viêm thị thần kinh ở trẻ em tại Bệnh viện Mắt trung ương trong 5 năm (2008-2012).
6. Ambika S., Padmalakshmi K., Venkatraman V., et al. (2018). Visual Outcomes and Clinical Manifestations of Pediatric Optic Neuritis in Indian Population: An Institutional Study. J Neuro-Ophthalmol Off J North Am Neuro-Ophthalmol Soc, 38(4), 462–465.
7. Absoud M., Cummins C., Desai N., et al. (2011). Childhood optic neuritis clinical features and outcome. Arch Dis Child, 96(9), 860–862.
8. Sri-udomkajorn S. and Pongwatcharaporn K. (2011). Clinical features and outcome of childhood optic neuritis at Queen Sirikit National Institute of Child Health. J Med Assoc Thail Chotmaihet Thangphaet, 94 Suppl 3, S189-194.
9. Yeh E.A., Graves J.S., Benson L.A., et al. (2016). Pediatric optic neuritis. Neurology, 87(9 Suppl 2), S53-58.