PHẪU THUẬT CẮT TOÀN BỘ TUYẾN GIÁP KẾT HỢP I131 ĐIỀU TRỊ UNG THƯ TUYẾN GIÁP THỂ BIỆT HÓA

Abstract

Objective: To evaluate the treatment results of differentiated thyroid cancer treated with total thyroidectomy combined with I¹³¹ therapy at Military Hospital 103. Subjects: 201 patients had been operated between September 2018 and October 2021, treated with I131 and followed up until April 2024. Method: retrospective, cross-sectional study. Results: Mean of age was 49.34±10.69 (21-72), female/male ratio was 4.7/1. Postoperative complications rate were 5.0%, of which recurrent laryngeal nerve injury was the highest (2.5%). The average follow-up time was 47.11±9.44 (26-67 months), with one patient died due to local tumor recurrence, tracheal invasion causing respiratory failure. The overall recurrence rate was 3.5%, metastasis rate was 1.5% (1 patient had metastasis to the lungs). Overall survival (OS) after 5 years was 99.5%, in which the 5-year OS rate of the patients group under 55 years old was 100%, the group of patients ≥ 55 years old was 99.2%. Conclusion: Total thyroidectomy combined with I¹³¹ therapy for treatment of differentiated thyroid cancer at Military Hospital 103 had positive results, with low recurrence and metastasis rates (3.5% and 1.5%), and 5-year OS of 99.5%.