TÌNH TRẠNG KHÁNG KHÁNG SINH CỦA CÁC VI KHUẨN PHÂN LẬP ĐƯỢC TỪ BỆNH PHẦM ĐƯỜNG HÔ HẤP TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI TRUNG ƯƠNG

Abstract

Objective: This study aimed to evaluate the etiology of lower respiratory tract infections and their antibiotic resistance. Subjects & Methods: A cross-sectional descriptive study was performed on 281 lower respiratory tract specimens from patients with pneumonia treated at National Hospital of Tropical Diseases from August 2022 to June 2024. Results: The positive culture rate of lower respiratory tract specimen samples was 43.4%. The four most commonly isolated bacterial pathogens were: A. baumannii 28%, P. aeruginosa 22.5%, K. pneumoniae 15.8%, and S. aureus 6.7%. A. baumannii was resistant to Cefepime (94.7%), Carbapenem (92.4%-93.3%), Quinolones (70%-89.1%), Aminoglycosides (79.6%-92.2%), and Penicillin (86.1%-93.6%). P. aeruginosa was resistant to Ceftazidime (58.1%), Cefepime (70.4%), Amikacin (82.1%), Quinolones (68.2%-78.1%), and Piperacillin/Tazobactam (68.9%). K. pneumoniae was resistant to third-generation Cephalosporins (60.4%-70.6%), Cefepime (62.7%), Carbapenem (48.7%-61.6%), Quinolones (57.1%-75%), and Penicillin (62%-100%). S. aureus was resistant to Aminoglycosides (33%), Quinolones (38.1%-40%), and Oxacillin (72.7%).