Article Sidebar

pdf
Date Published: 23/06/2025
Abstract Views: 51
Views pdf: 29
DOI: https://doi.org/10.51298/vmj.v551i1.14478
Issue
Vol. 551 No. 1 (2025)
Section
Các bài báo
How to Cite
Nguyễn Tiến, D., & Hoàng Văn, V. (2025). ASSESSMENT OF CHANGES IN SELECTED LABORATORY TESTS AND SOFA SCORES IN SEVERE BURN PATIENTS RESUSCITATED AND MANAGED WITH USCOM. Vietnam Medical Journal, 551(1). https://doi.org/10.51298/vmj.v551i1.14478

ASSESSMENT OF CHANGES IN SELECTED LABORATORY TESTS AND SOFA SCORES IN SEVERE BURN PATIENTS RESUSCITATED AND MANAGED WITH USCOM

Dũng Nguyễn Tiến, Vụ Hoàng Văn

Main Article Content

Abstract

Objective: To evaluate changes in selected laboratory parameters and SOFA scores in severe burn patients treated under USCOM-guided fluid resuscitation. Methods: A cross-sectional study was conducted on 30 severe burn patients admitted to the Intensive Care Unit of the National Burn Hospital within the first 8 hours post-burn, from August 2023 to May 2024. Patients underwent fluid resuscitation guided by USCOM. Blood lactate levels, hematocrit, hemoglobin, arterial blood gases, and SOFA scores were measured at admission (T0), 24 hours (T2), 48 hours (T3), and 72 hours (T4) post-burn. Results: Blood lactate levels were initially elevated (>2.0 mmol/L) and gradually decreased, reaching the target level after 48 hours. Hematocrit and hemoglobin levels were initially high but decreased over time, reaching their lowest levels at 72 hours. Arterial blood gases showed an initial mild decrease in blood pH, HCO3-, and base excess (BE), followed by improvement and normalization. PaO2 levels gradually increased, while PaCO2 levels decreased. The SOFA score was initially high (>2) but gradually decreased to normal levels after 48 hours. Conclusion: USCOM-guided fluid resuscitation effectively improved blood lactate levels, hematocrit, and hemoglobin, corrected acid-base imbalances, and reduced the risk of organ failure in severe burn patients.

Article Details

Keywords

Severe burns, fluid resuscitation, blood lactate, hematocrit, hemoglobin, arterial blood gases, SOFA score

References

1. Singer M., Deutschman C.S., Seymour C.W., et al. (2016), "The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)." JAMA.
2. Rhodes A., Evans L.E., Alhazzani W., et al. (2017), "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016." Critical Care Medicine.
3. Pinsky M.R. (2015). "Hemodynamic monitoring in the critically ill." New England Journal of Medicine.
4. Perel A. (2017), "Non-invasive cardiac output monitoring: a state of the art review." Journal of Clinical Monitoring and Computing.
5. Vincent J.L., Moreno R., Takala J., et al. (1996). "The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/ failure." Intensive Care Medicine; 22(7): 707-710.
6. Vincent J.L. (2019). "Understanding cardiac output." Critical Care.
7. Nguyen H.T., Tran T.P., Le V.D. (2021). "Epidemiology of Severe Burns in Vietnam." Vietnam Journal of Emergency Medicine; 10(3): 112-118.
8. Barton R. G., Saffle J. R., Morris S. E., et al. (1997). "Resuscitation of thermally injured patients with oxygen transport criteria as goals of therapy." The Journal of Burn Care & Rehabilitation; 18(1): 1-9.
9. Holm C., Mayr M., Tegeler J., et al. (2004). "A clinical randomized study on the effects of invasive monitoring on burn shock resuscitation." Burns; 30(8): 798-807.
10. O’Mara M. S., Slater H., Goldfarb I. W., et al. (2005). "A prospective, randomized evaluation of intra-abdominal pressures with crystalloid and colloid resuscitation in burn patients." Journal of Trauma and Acute Care Surgery; 58(5): 1011-1018.