INVESTIGATION OF THE ASSOCIATION BETWEEN SERUM SODIUM LEVELS AND SHORT-TERM ADVERSE EVENTS IN PATIENTS WITH ACUTE DECOMPENSATED CHRONIC HEART FAILURE WITH REDUCED EJECTION FRACTION

Hòa Trần, Dũng Bùi Thế, Hà Nguyễn Hồng

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Abstract

Objectives: To evaluate the prognostic value of serum sodium levels for short-term outcomes in patients with acute decompensated heart failure with reduced ejection fraction. Materials and methods: A descriptive cross-sectional study was conducted at the Can Tho Central General Hospital from March 2024 to March 2025. Patients were monitored for short-term events including rehospitalization due to heart failure and all-cause mortality within 1 month. Results: A total of 85 patients were enrolled, with a mean age of 64.25 ± 13.45 years. The rates of heart failure, rehospitalization and mortality were 21.2% and 14.1%. Hyponatremia, diabetes mellitus, and NYHA classification on admission were independent predictors of the composite short-term outcome with HR = 9.89, HR = 7.54, and HR = 5.29. Conclusion: Patients with acute decompensated chronic heart failure with reduced ejection fraction exhibited a relatively high rate of short-term adverse events. Hyponatremia, along with diabetes mellitus and NYHA functional class at admission, were independent predictors of increased risk for these short-term outcomes.

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References

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