APPLICATION OF ARTIFICIAL INTELLIGENCE IN ASSISTING LUNG CANCER DIAGNOSIS THROUGH CHEST COMPUTED TOMOGRAPHY IMAGING

Thảo Nguyễn Thị Thu, Lượng Trần Văn, Long Trần Quốc, Bá Lương Sơn, Du Phạm Tiến, Huỳnh Trịnh Ngọc, Lưu Vũ Đăng, Giáp Vũ Văn

Main Article Content

Abstract

Objective: To evaluate the effectiveness of the artificial intelligence (AI) application developed at Bach Mai Hospital in collaboration with Vietnam National University, Hanoi, in diagnosing lung cancer based on chest computed tomography (CT) images, compared to the assessments of medical experts. Subjects and Methods: A descriptive study involving 200 patients (100 histologically confirmed lung cancer cases, 100 non-cancer cases) at Bach Mai Hospital. Recorded lesion features included location, size, border characteristics, calcification, and cavitation (malignant group); consolidation, ground-glass opacity, and tree-in-bud lesions (benign group). Statistical measures included sensitivity, specificity, accuracy, and receiver operating characteristic (ROC) curve analysis using SPSS 23 (significance level p<0.05). The study was approved by the Biomedical Ethics Committee (733/BM-HĐĐĐ). Results: The AI achieved a sensitivity of 90%, specificity of 91%, and accuracy of 90%. The AI model performed well with benign lesions and solitary pulmonary nodules but had limitations in assessing calcification and cavitation, often confusing tumors with inflammatory lesions, particularly in rare disease forms. Conclusion: AI shows promising potential but still has limitations that require improvement before widespread clinical application.

Article Details

References

1. Jia Y, Gong W, Zhang Z, et al. Comparing the diagnostic value of 18F-FDG-PET/CT versus CT for differentiating benign and malignant solitary pulmonary nodules: a meta-analysis. J Thorac Dis. 2019;11(5). doi:10.21037/jtd.2019.05.21
2. Gandhi Z, Gurram P, Amgai B, et al. Artificial Intelligence and Lung Cancer: Impact on Improving Patient Outcomes. Cancers. 2023; 15(21):5236. doi:10.3390/cancers15215236
3. Schreuder A, Scholten ET, Ginneken B van, Jacobs C. Artificial intelligence for detection and characterization of pulmonary nodules in lung cancer CT screening: ready for practice? Transl Lung Cancer Res. 2021;10(5). doi:10.21037/tlcr-2020-lcs-06
4. Ardila D, Kiraly AP, Bharadwaj S, et al. End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nat Med. 2019;25(6):954-961. doi:10.1038/s41591-019-0447-x
5. Cellina M, Cacioppa LM, Cè M, et al. Artificial Intelligence in Lung Cancer Screening: The Future Is Now. Cancers. 2023;15(17):4344. doi:10.3390/ cancers15174344
6. Huang D, Li Z, Jiang T, Yang C, Li N. Artificial intelligence in lung cancer: current applications, future perspectives, and challenges. Front Oncol. 2024;14. doi:10.3389/fonc.2024.1486310
7. Khalifa M, Albadawy M. AI in diagnostic imaging: Revolutionising accuracy and efficiency. Comput Methods Programs Biomed Update. 2024;5: 100146. doi:10.1016/j.cmpbup.2024. 100146
8. Kim RY, Oke JL, Pickup LC, et al. Artificial Intelligence Tool for Assessment of Indeterminate Pulmonary Nodules Detected with CT. Radiology. 2022;304(3):683-691. doi:10.1148/radiol.212182