INITIAL ASSESSMENT OF BIOPSY RESULTS IN PATIENTS WITH PROSTATE HYPERPLASIA WITH INCREASED TOTAL PROSTATE SPECIFIC ANTIGEN AT BACH MAI HOSPITAL

Dũng Nghiêm Trung, Hà Đặng Thị Việt, Minh Vũ Công, Hiếu Nguyễn Trung

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Abstract

Objective: According to EAU 2019, prostate biopsy under transrectal ultrasound (TRUS) guidance is a crucial technique for early detection and is considered the gold standard for diagnosing prostate cancer. Therefore, to evaluate the results of prostate biopsy and explore the relationship between biopsy outcomes and other factors, we conducted this study. Research Objectives: To assess biopsy results and compare them with relevant factors at Bach Mai Hospital. Subjects and Research Methods: A cross-sectional descriptive study was conducted on 105 patients with benign prostatic hyperplasia (BPH) with total PSA > 4 ng/ml, who were indicated for prostate biopsy from July 2022 to March 2025. Results: The average age was 71.38 ± 7.26 years, with the oldest being 87 years and the youngest 55 years. The majority of patients were aged between 61-80 years. The cancer detection rate in this study was 55.2%. There was a statistically significant correlation between total PSA levels, MRI lesion classification according to PIRADS, and the location of prostate lesions with biopsy results. Conclusion: Prostate biopsy is recommended for individuals with: (1) Total PSA > 10 ng/ml or free PSA/total PSA ratio < 0.25 in patients with total PSA < 10 ng/ml, (2) MRI-identified lesions classified as PIRADS IV or higher, (3) Lesions located in the peripheral zone or involving both the transition and peripheral zones of the prostate

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