ĐẶC ĐIỂM TẾ BÀO MÁU NGOẠI VI Ở NGƯỜI BỆNH XƠ GAN ĐIỀU TRỊ TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI TRUNG ƯƠNG GIAI ĐOẠN 2021 – 2022

Abstract

Objectives: Description of the characteristics of certain peripheral blood cell test parameters and their correlation with the severity of cirrhosis in cirrhotic patients examined and treated at the National Hospital for Tropical Diseases. Subjects and Methods: Analysis of 109 medical records of cirrhotic patients treated at the National Hospital for Tropical Diseases from April 2021 to March 2022. A retrospective descriptive study. Results: The average age of cirrhotic patients was 54.39 ± 11.41 years, with males accounting for 80.7% and females 19.3%. The highest proportion of patients was classified as Child-Pugh C (39.4%), followed by Child-Pugh B (34.9%), and the lowest was Child-Pugh A (25.7%). The primary cause of cirrhosis was HBV (67%). Anemia was observed in 55% of patients, predominantly normochromic anemia. The mean corpuscular volume (MCV) was 100.83 ± 11.21 fl, and the red cell distribution width (RDW) was 18.48 ± 4.46%. The white blood cell (WBC) count was 6.65 ± 3.07 G/L, with no significant differences among Child - Pugh groups. Thrombocytopenia was found in 84.4% of patients, particularly in the Child-Pugh C group. Red blood cell count, hemoglobin, and platelet levels progressively decreased with increasing severity of cirrhosis (p < 0.05). Conclusion: Anemia and thrombocytopenia are common hematological abnormalities in cirrhotic patients, with the degree of alteration correlating with the severity of liver damage. Monitoring hematological parameters is crucial for assessing and prognosticating cirrhotic patients.