ĐẶC ĐIỂM CÁC DẤU ẤN HBV Ở BỆNH NHÂN NHIỄM HBV MẮC U LYMPHO TẠI TRUNG TÂM HUYẾT HỌC VÀ TRUYỀN MÁU BỆNH VIỆN BẠCH MAI

Abstract

Objectives: Describe HBV (Hepatitis B Virus) markers of HBV-infected patients with lymphoma. Methods: A Cross-sectional descriptive study of 25 HBV-infected patients with lymphoma treated at Hematology and Blood Transfusion Center – Bach Mai Hospital. Results: 23/25 patients were diagnosed with non-Hodgkin lymphoma; male (78%); mean age was 53,1±14,2. Patients with HBsAg positive accounted for 76%, 24% remaining were belonged to the HBsAg negative and anti-HBc total positive. HBeAg and anti-HBe were positive in 23,5% and 35,3% of tested patients, respectively. HBV-DNA was detected in 85% regardless of HBsAg status in tested patients, with the lowest level was 1,69 logIU/ml, the highest was 8,59 logIU/ml, and the mean was 4,38 logIU/ml. We recorded 1 case with HBsAg negative, anti-HBs positive and HBV-DNA’s serum was detected. Conclusion: In our study, the proportion of HBsAg-positive patients was higher than that of HBsAg-negative, anti-HBc total positive patients with lymphoma. A full test for the first screening was required before lymphoma’s treatment to avoid missing patients who need to be prevented.