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SUMMARY EPIDEMIOLOGICAL, CLINICAL CHARACTERISTICS, AND TREATMENT OUTCOMES OF ACUTE DIARRHEA CAUSED BY ROTAVIRUS IN CHILDREN AGED 6 MONTHS TO 5 YEARS AT SÓC TRĂNG OBSTETRICS AND PEDIATRICS SPECIALTY HOSPITAL
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Abstract
Background: Rotavirus is the leading cause of severe acute diarrhea requiring hospitalization in young children. Objectives: To study the epidemiological and clinical characteristics as well as treatment outcomes of acute diarrhea caused by Rotavirus in children aged 6 months to 5 years at Sóc Trăng Obstetrics and Pediatrics Specialty Hospital. Subjects and Methods: A total of 106 stool samples from children aged 6 months to 5 years diagnosed with acute diarrhea and treated at Soc Trang Obstetrics and Pediatrics Specialty Hospital from August 2024 to February 2025 were tested for Rotavirus infection using the ELISA technique. Results: The prevalence of Rotavirus infection was 47%. The average age of children with acute diarrhea caused by Rotavirus was 17.34 ± 8.25 months, with 58% being male. 70% of cases were from rural areas, while 30% were from urban areas. Ethnic distribution included 42% Kinh and 50% Khmer. The most common clinical symptoms during the acute phase were vomiting (90%), fever (76%). Among these, 50% presented with diarrhea + fever + vomiting, and 40% had diarrhea + vomiting. Upon hospital admission, 56% of children had fever, mostly mild (≤ 38.5°C in 75% of cases) and lasting less than 3 days (55.3%). The frequency of diarrhea ranged mostly between 10–20 times per day (32%), with an average duration of diarrhea lasting 4.34 ± 1.59 days. The proportion of children with no dehydration was 72%, mild to moderate dehydration was 26%, and severe dehydration was 2%. The mean Vesikari score was 13.08 ± 1.86, and 88% of children had severe disease. The average hospital stay was 5.18 ± 1.91 days. The recovery rate was 100%. Conclusion: Rotavirus is a common cause of acute diarrhea in children aged 6 months to 5 years. 88% of acute diarrhea caused by Rotavirus was severe according to Vesikari classification, and 26% had dehydration according to WHO.
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Keywords
Rotavirus, Acute diarrhea
References
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