CLINICAL CHARACTERISTICS, RADIOLOGICAL FEATURES AND TREATMENT OUTCOME OF ACUTE ISCHEMIC STROKE IN YOUNG ADULTS AT THE BACH MAI HOSPITAL

Hoàng Trọng Tuệ1,, Mai Duy Tôn2, Nguyễn Anh Tuấn2, Nguyễn Anh Tuấn2, Đào Việt Phương2
1 Ha Dong General Hospital
2 Bach Mai Hospital

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Abstract

Objectives: Clinical characteristics, radiological features and treatment outcome of acute ischemic stroke in young adults (18 - 45 years) at the Bach Mai hospital. Methods: This study retrospectively reviewed the records of all 18 to 45-year-old patients who were admitted to the Emergency Department and Stroke center of Bach Mai hospital from November 2019 to June 2021. The three months clinical outcome was evaluated using the modified Rankin scale (mRS) score. The mRS score was used to classify clinical outcome as favourable (score 0-1) or unfavourable (score 2-6).  Results: There were 91 patients, 63 men (69.8%) and 29 women: with a mean age of 37.62 ± 5.83 years (range 18–45 years). Stroke of large-artery atherosclerosis 31.9% was the most common subtype, whereas other determined etiology (10.9%). Among all the patients, 42 (46.2%) arrived at hospital within 6 hours of stroke onset, and the number of patients who were admitted to hospital > 6 hours after stroke onset, 49 (53.8%). In the survey of risk factors, the common risk factors were hyperlipidemia 24.2%, hypertension 19.8%, overweight 12.2%, atrial fibrillation 11%, diabetes mellitus 3.3%. At three months hospital discharge, favorable (mRS:0-1) and unfavorable outcomes (mRS 2-6) had incidences of 79.1% and 20.9%, respectively, mortality was 5.5%. Conclusions: Our study found that ischemic stroke of young adults patients at Bach Mai hospital had a good outcome at three months hospital discharge.

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References

1. Mozaffarian D et al, Heart disease and stroke statistics-2015 update: a report from the American Heart Association. ahajournals. 2015,131(4):e29-322.
2. Feigin VL et al, Update on the global burden of ischemic and hemorrhagic stroke in 1990–2013: the GBD 2013 study. Neuroepidemiology. 2015; 45:161–76.
3. Adams Jr HP, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. stroke. 1993; 24(1):35-41.
4. Ji R, Schwamm LH, Pervez MA, Singhal AB. Ischemic stroke and transient ischemic attack in young adults: risk factors, diagnostic yield, neuroimaging, and thrombolysis. JAMA neurology. 2013;70(1):51-7.
5. Kwon SU, Kim JS, Lee JH, Lee MC. Ischemic stroke in Korean young adults. Acta Neurol Scand. 2000;101:19–24.
6. Lee TH, Hsu WC, Chen CJ, Chen ST. Etiologic study of young ischemic stroke in Taiwan. Stroke. 2002;33(8):1950-1955.