NGHIÊN CỨU TÌNH HÌNH TĂNG NON-HDL-C VÀ MỐI LIÊN QUAN VỚI TỔN THƯƠNG HẸP MẠCH VÀNH Ở BỆNH NHÂN HỘI CHỨNG VÀNH CẤP CÓ ĐẶT STENT MẠCH VÀNH

Abstract

Background: Current literature suggests that non-HDL-C cholesterol (non-HDL-C) levels are associated with prognosis in patients with acute coronary syndrome (ACS) undergoing coronary stenting. However, unlike LDL-C, existing studies have shown inconsistent results, particularly in Vietnam. Objectives: To determine the prevalence of elevated serum non-HDL-C levels and the association with coronary artery stenosis in ACS patients undergoing coronary stenting. Materials and methods: A cross-sectional descriptive study was conducted on 112 ACS patients undergoing coronary stenting at Thong Nhat Dong Nai General Hospital. Results: The female-to-male ratio was 1.8:1, with a mean age of 67.14 ± 13.46 years, and the majority of patients were over 60 years old. The prevalence of overweight and obesity was 45.5%. Regarding lifestyle habits, 55.4% of patients were smokers, and 84.8% had a sedentary lifestyle. Among comorbidities, 84.8% had hypertension, and 28.6% had diabetes mellitus. The proportion of patients with non-HDL-C levels above 2.6 mmol/L was 76.8%. In the group with non-HDL-C >2.6 mmol/L, the number of affected coronary vessels was higher than in the group with non-HDL-C ≤2.6 mmol/L (3.42 ± 1.17 vs. 2.8 ± 1.18 vessels, 95% CI: 0.62 (0.1–1.14)), with a statistically significant difference (p = 0.02). Conclusion: The majority of ACS patients undergoing coronary stenting had elevated non-HDL-C levels. There was a statistically significant association between the number of affected coronary vessels and non-HDL-C levels in this patient population.