SURVEY OF SOME CLINICAL AND RELATED CLINICAL-LABORATORY INDICATORS AMONG PREGNANT WOMEN WITH HIGH RISKS OF PRE-ECLAMPSIA AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL
Main Article Content
Abstract
Objective: To assess the prevalence of preeclampsia (PE) among pregnant women presenting with abnormal conditions during pregnancy at Hanoi Obstetrics and Gynecology Hospital. Method: A retrospective descriptive study was conducted on 128 pregnant women exhibiting abnormal pregnancy conditions who were examined and followed up at Hanoi Obstetrics and Gynecology Hospital. Results: The prevalence of PE was 55.47% among the study participants (n = 71/128), of which 28.16% were classified as severe PE. The incidence of hypertension (HTN) was 76.42%, with a mean blood pressure of 142.07±20.63/89.16±13.18 mmHg. Headache was the most common accompanying symptom, reported in 19.53% of cases, 30.99% had fetuses with intrauterine growth restriction (IUGR). The average uric acid level was 401.33±105.58. The sFlt-1/PlGF ratio, with a relatively high sensitivity of 79% (95% CI, 0.68-0.87). Conclusion: HTN was the most frequent clinical manifestation observed in pregnant women at high risk for PE. Preeclampsia was linked to a higher risk of fetal growth restriction. The sFlt-1/PlGF ratio demonstrated potential utility in supporting the early diagnosis of PE.
Article Details
Keywords
Preeclampsia, hypertension, sFlt-1/PLGF ratio
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