PHÂN TÍCH TÌNH HÌNH SỬ DỤNG THUỐC TRÊN BỆNH NHÂN VIÊM KHỚP TẠI BỆNH VIỆN ĐA KHOA CẦN THƠ 2023

Abstract

Introduction: Arthritis is a common musculoskeletal disorder affecting both men and women, especially in middle-aged individuals. In Vietnam, approximately 700 people per million suffer from this condition. Arthritis not only damages joints but can also affect the heart, lungs, and nervous system, and may lead to disability if not treated promptly. Although it does not directly cause death, it can significantly reduce quality of life and work capacity. Current treatment includes various drug classes such as NSAIDs, corticosteroids, and opioids; however, caution is required due to potential adverse effects, particularly on the gastrointestinal tract. Early diagnosis and appropriate treatment are essential for effective disease control. Objective: To investigate the clinical characteristics of arthritis in patients and to assess the current status of drug utilization in the treatment of osteoarthritis at Can Tho General Hospital. Subjects and Methods: This was a cross-sectional descriptive, non-controlled study conducted on 100 prescriptions collected from arthritis patients treated at Can Tho General Hospital in 2021. Results: A review of 100 prescriptions from arthritis patients at Can Tho General Hospital (January–June 2023) showed that the disease predominantly affected individuals aged 61 years and older (56%), with a higher prevalence in females (76%). The study sample comprised 11 types of arthritis, with generalized osteoarthritis being the most common (58%), followed by spondyloarthritis (10%) and rheumatoid arthritis (9%). All patients had comorbidities, the most common being gastroesophageal reflux disease (48%) and metabolic disorders (22%). Regarding treatment, 89% of patients were prescribed paracetamol for pain relief, and 90% received non-steroidal anti-inflammatory drugs (NSAIDs), mainly celecoxib (49%) and meloxicam (5%). The use of NSAIDs followed the principle of not combining drugs from the same class simultaneously. These findings reflect the degenerative nature of arthritis in the elderly, the high rate of comorbidities, and the current trend toward effective and safe treatment approaches. Conclusion: The study shows that arthritis is more prevalent among older adults, especially women, with generalized osteoarthritis being the most common form. Most patients had comorbid conditions, primarily gastroesophageal reflux disease and metabolic disorders. The use of analgesics and NSAIDs was appropriately prescribed, adhering to recommended treatment principles. This reflects a treatment trend focused on balancing efficacy and safety, particularly in elderly patients.