APPLICATION OF SHOCK INDEX IN PREDICTING IN-HOSPITAL MORTALITY IN PATIENTS WITH ACUTE HEART FAILURE

Hải Nguyễn Hoàng, Duẫn Phan, Bình Trương Quang

Main Article Content

Abstract

Background: The Shock Index (SI), calculated as the ratio between heart rate and systolic blood pressure, serves as a straightforward mathematical formula. It has demonstrated prognostic significance in non-cardiac conditions across various studies utilizing different threshold values. While the global application of SI in acute heart failure has been explored, data specific to its use in Vietnam remains limited. Objects and methods: This retrospective descriptive study was conducted on patients admitted with acute heart failure at Nhan dan Gia Định Hospital, utilizing the diagnostic criteria from the Vietnam National Heart Association (VNHA) 2022 guidelines. The primary outcome was in-hospital mortality. Multivariate logistic regression analysis was employed to identify independent predictors of in-hospital mortality. Results: Among 115 acute heart failure patients: A cut-off SI of 0.908 demonstrated high predictive accuracy for in-hospital mortality, with an area under the ROC curve (AUC) of 0.88 and a negative predictive value of 98.91%. Multivariate logistic regression analysis established SI as an independent predictor of in-hospital events and mortality in acute heart failure patients. Additionally, elevated low-density lipoprotein cholesterol (LDLc) levels and the presence of acute coronary syndrome were identified as independent predictors of in-hospital mortality in patients with acute heart failure. Conclusion: The Shock Index (SI) is a simple, rapid, and convenient tool that contributes to the prediction of in-hospital mortality in patients with acute heart failure.

Article Details

References

1. Chioncel O, Mebazaa A, Harjola VP, et al. Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long-Term Registry. Eur J Heart Fail. Oct 2017;19(10):1242-1254. doi:10.1002/ejhf.890
2. Chioncel O, Mebazaa A, Maggioni AP, et al. Acute heart failure congestion and perfusion status - impact of the clinical classification on in-hospital and long-term outcomes; insights from the ESC-EORP-HFA Heart Failure Long-Term Registry. Eur J Heart Fail. Nov 2019;21(11):1338-1352. doi:10.1002/ejhf.1492
3. Miro O, Garcia Sarasola A, Fuenzalida C, et al. Departments involved during the first episode of acute heart failure and subsequent emergency department revisits and rehospitalisations: an outlook through the NOVICA cohort. Eur J Heart Fail. Oct 2019;21(10):1231-1244. doi:10.1002/ ejhf.1567
4. Crespo-Leiro MG, Anker SD, Maggioni AP, et al. European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions. Eur J Heart Fail. Jun 2016;18(6):613-25. doi:10.1002/ ejhf.566
5. Tomasoni D, Lombardi CM, Sbolli M, Cotter G, Metra M. Acute heart failure: More questions than answers. Prog Cardiovasc Dis. Sep-Oct 2020;63(5):599-606. doi:10.1016/j.pcad.2020.04.007
6. Lee DS, Straus SE, Farkouh ME, et al. Trial of an Intervention to Improve Acute Heart Failure Outcomes. N Engl J Med. Jan 5 2023;388(1):22-32. doi:10.1056/NEJMoa2211680
7. Tran DT, Ohinmaa A, Thanh NX, et al. The current and future financial burden of hospital admissions for heart failure in Canada: a cost analysis. CMAJ Open. Jul-Sep 2016;4(3):E365-E370. doi:10.9778/cmajo.20150130
8. Lesyuk W, Kriza C, Kolominsky-Rabas P. Cost-of-illness studies in heart failure: a systematic review 2004-2016. BMC Cardiovasc Disord. May 2 2018;18(1):74. doi:10.1186/ s12872-018-0815-3
9. Đỗ Thị Nam Phương, Nguyễn Anh Duy Tùng. Khảo sát các yếu tố tiên lượng tử vong trên bệnh nhân suy tim phân suất tống máu giảm nhập viện tại Viện Tim TP Hồ Chí Minh. Tạp chí Tim mạch học Thành phố Hồ Chí Minh. 2019
10. Hội Tim mạch học Quốc gia Việt Nam. Khuyến cáo về chẩn đoán và điều trị suy tim cấp và mạn tính. 2022