ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH NHÂN ĐA U TỦY XƯƠNG TẠI BỆNH VIỆN K

Abstract

Objective: Describe the clinical and paraclinical characteristics of multiple myeloma’s patients treated with Bortezomib at K Hospital; Subjects and methods: Cross-sectional descriptive study conducted on 76 multiple myeloma’s patients treated with bortezomib regimen at the Hematologic Oncology Department, K Hospital from May 2019 to October 2022. Results: The average age of patients was 58.76, the male/female ratio was 0.9, Almost patients had PS=0-1 accounting for 72.4%, Almost patients were hospitalized because of bone pain accounting for 84%, Almost patients have multiple lesions accounting for 85.5%. The most common bone lesions were in the lumbar spine 65.8%, the proportion of patients with hemoglobin ≤ 100 g/L was 50.0%, the proportion of patients with plasma cell in the marrow ≥ 10% was 63.2%, the proportion of patients had increased creatinine ≥ 177 umol/L was 5.3%, the proportion of patients had increased total calcium ≥ 2.75 mmol/L was 3.9%, the most common myeloma type was IgG Kappa 32.9%, IgG Lambda 26.3%, Stage II according to ISS accounted for the highest proportion 41%. Conclusion: Research shows characteristic clinical and paraclinical symptoms of multiple myeloma that support doctors in the diagnosis and treatment process