NHẬN XÉT KẾT QUẢ SÀNG LỌC SƠ SINH BỆNH LÝ SUY GIÁP BẤM SINH TẠI BỆNH VIỆN PHỤ SẢN HÀ NỘI

Abstract

Congenital hypothyroidism is a common endocrine disorder caused by insufficient production of thyroid hormones necessary for a child’s development. If not detected and treated in time, the condition can lead to physical and intellectual developmental delays. Objective: This study aims to evaluate the results of neonatal screening for congenital hypothyroidism using heel-prick blood samples at Hanoi Obstetrics and Gynecology Hospital. Subjects and Methods: The study was conducted on 35,360 newborns screened for congenital hypothyroidism at Hanoi Obstetrics and Gynecology Hospital from June 2023 to May 2024. This is a cross-sectional descriptive study using a screening test that measures TSH levels on filter paper. Data were collected, processed, and analyzed using SPSS 20.0 statistical software. Conclusion: The positive screening rate was 1 in 1,072 newborns, with a confirmed diagnosis rate of congenital hypothyroidism at 1 in 1,415 newborns. The positive predictive value of the test was 63,7%. The study confirms the importance of neonatal screening programs in the early detection of congenital hypothyroidism, enabling timely intervention, improving disease prognosis, and reducing the risk of physical and intellectual developmental delays. To enhance screening effectiveness, follow-up and repeated testing are recommended for high-risk infants to minimize false-negative cases.