COMPARISON OF POST-ENDODONTIC PAIN IN TEETH WITH PERIAPICAL LESIONS: BIOROOT™ RCS VS. AH PLUS®

Mỹ Nguyễn Phan Hoài, Quang Nguyễn Nhật, Vĩnh Trần Xuân

Main Article Content

Abstract

Objectives: To compare the levels of spontaneous pain and pain on biting after root canal obturation with either a calcium silicate-based sealer (BioRoot™ RCS) or a resin-based sealer (AH Plus®) at 6, 12, 24, and 72 hours post-obturation. Subject and methods: This was a randomized controlled clinical trial conducted on 40 single-rooted teeth from 32 patients diagnosed with periapical lesions. The patients were evenly divided into two groups of 20 teeth each. Group 1 received root canal obturation with calcium silicate-based sealer (BioRoot ™ RCS), while Group 2 received resin-based sealer (AH Plus®). The study was conducted at District 1 Hospital, Ho Chi Minh City. Pain levels were assessed after obturation using the Visual Analog Scale (VAS). Results: The average age of participants was 53.6 years, with females accounting for 35% of the sample. A total of 37.5% of patients presented with periapical abscesses. After three months, 100% of the treated teeth showed resolution of abscesses and no remaining clinical signs. The highest average levels of spontaneous pain and pain on biting were recorded immediately after root canal obturation (Group 1: 2.9 and 3.0 points; Group 2: 2.9 and 3.6 points, respectively). Pain levels decreased progressively at 6, 12, and 24 hours, reaching their lowest at 72 hours (Group 1: 0 points; Group 2: 0.3 points) (p < 0.05). Conclusion: Calcium silicate-based sealer (BioRoot™ RCS) demonstrated clinical effectiveness comparable to epoxy resin-based sealer (AH Plus®) in the treatment of chronic periapical lesions.

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References

1. Vibha Rahul Hegde, Sanitra Rahul Hegde, Ushaina Eruch Fanibunda, Meghana Aditya Vartak (2025). “Comparative evaluation of postoperative pain and healing following root canal obturation with calcium silicate and bioactive glass-based sealers to epoxy resin-based sealers: A systematic review and meta-analysis” J Conserv Dent Endod 2025 Mar;28(3): 211-221. doi: 10.4103/JCDE.JCDE_8_25. Epub 2025 Mar 3.
2. Sanz JL, López-García S, Rodríguez-Lozano FJ, Melo M, Lozano A, Llena C, Forner L. Cytocompatibility and bioactive potential of AH Plus Bioceramic Sealer: An in vitro study. Int Endod J. 2022 Oct;55(10):1066-1080. doi: 10.1111/iej.13805. Epub 2022 Aug 11. PMID: 35950780; PMCID: PMC9541143.
3. Ziada, Saida & Aguir Mabrouk, Najet & Benneji, Takieddine & Sahtout, Saida (2023). An in vitro Evaluation of pH Variation and calcium ion release of three Endodontic Sealing Cements: BioRoot RCS, MTA Fillapex, and Acroseal. The Open Dentistry Journal. 17. 10.2174/ 0118742106257034231013044700.
4. Kirthiga M, Thomas G, Jose S, Adarsh VJ, Nair S. Antimicrobial efficacy of calcium silicate-based bioceramic sealers against Enterococcus faecalis and Staphylococcus aureus - An in vitro study. J Conserv Dent Endod. 2024 Jul;27(7):737-742. doi: 10.4103/JCDE.JCDE_215_24. Epub 2024 Jul 8. PMID: 39262595; PMCID: PMC11385916.
5. Lý Nguyễn Bảo Khánh (2017). Hiệu quả trám bít ống tủy chân răng của xi măng Calcium Silicate: nghiên cứu In Vitro, Luận văn thạc sĩ y học, Đại học Y Dược Thành Phố Hồ Chí Minh.
6. Khandelwal A, Jose J, Teja KV, Palanivelu A. Comparative evaluation of postoperative pain and periapical healing after root canal treatment using three different base endodontic sealers - A randomized control clinical trial. J Clin Exp Dent. 2022 Feb 1;14(2):e144-e152. doi: 10.4317/ jced.59034. PMID: 35173897; PMCID: PMC8842288.
7. V Vijith, Anarasi Mahaprasad, A Purusothaman, Aravind Kumar Duraivel, Mariea Francis, Hitesh Chohan (2024). “Comparative Evaluation of Sealing Ability, Bond Strength, and Antimicrobial Properties of Endodontic Sealers: An In Vitro Study” J Pharm Bioallied Sci. 2024 Dec 12;16(Suppl 4):S3942–S3944. doi: 10.4103/jpbs.jpbs_1110_24
8. Radwanski, M., Rozpedek-Kaminska, W., Galita, G. et al. Cytotoxicity and genotoxicity of bioceramic root canal sealers compared to conventional resin-based sealer. Sci Rep 14, 4124 (2024). https://doi.org/10.1038/s41598-024-54726-1