THE RESULTS OF SURGICAL TREATMENT OF THE BREAST CANCER AT QUANG NINH GENERAL HOSPITAL
Main Article Content
Abstract
Objective: To evaluate the results of surgical treatment of the breast cancer at Quang Ninh General Hospital. Methods: A combined retrospective and prospective study on 78 female patients with stage I–III breast cancer treated at the Oncology Department of Quang Ninh General Hospital from January 2017 to December 2022. Results: The mean age was 58.23 ± 11.9. The most common tumor location was the upper outer quadrant (53,6%). 41% of patients had postoperative axillary lymph node metastasis. The average number of lymph nodes dissected was relatively high, at 11.37 ± 4.49, with an average of 1.74 ± 3.78 metastatic nodes. The 5-year overall survival (OS) and disease-free survival (DFS) rates were 74% and 68%, respectively. Axillary lymph node metastasis, tumor size, and disease stage were significantly associated with both OS and DFS. Recurrence occurred in 18 patients, with the most common metastatic sites being the lungs (44.4%) and bones (38.9%). Conclusion: Surgery remains the primary treatment modality for stage I–III breast cancer. Axillary lymph node status, tumor size, and disease stage are important prognostic factors for overall survival and disease-free survival.
Article Details
Keywords
Breast cancer, surgery, OS, DFS
References
2. Đỗ Thị Kim Anh TVT. Đánh giá kết quả điều trị bổ trợ phác đồ 4AC - 4 Paclitaxel trên bệnh nhân ung thư vú giai đoạn II-III. Tạp chí Ung thư học Việt Nam. 2008;(1):260-266.
3. Trần Văn Thuấn NBĐ. So sánh hiệu quả phác đồ CMF và CAF trong điều trị bổ trợ ung thư vú giai đoạn II, III. Tạp chí Y học thực hành. 2002;(431):232-236.
4. Trần Văn Thuấn. Đánh giá kết quả của phương pháp điều trị hóa chất sau mổ CMF trong ung thư vú giai đoạn II-III tại bệnh viện K từ 1994-1998. Đại học Y Hà Nội. Published online 2001.
5. Nguyễn Văn Quy. Nghiên cứu chẩn đoán và điều trị ung thư vú giai đoạn I-III ở phụ nữ tại bệnh viện đa khoa Cần Thơ. Đại học Y Hà Nội. Published online 2007.
6. Carter CL, Allen C, Henson DE. Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases. Cancer. 1989;63(1): 181-187. doi:10.1002/1097-0142(19890101)63:1 <181::aid-cncr2820630129>3.0.co;2-h
7. Park BW, Kim SI, Kim EK, Yang WI, Lee KS. Impact of patient age on the outcome of primary breast carcinoma. J Surg Oncol. 2002;80(1):12-18. doi:10.1002/jso.10088
8. Mirza AN, Mirza NQ, Vlastos G, Singletary SE. Prognostic factors in node-negative breast cancer: a review of studies with sample size more than 200 and follow-up more than 5 years. Ann Surg. 2002;235(1):10-26. doi:10.1097/00000658-200201000-00003