ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG Ở BỆNH NHÂN SUY HÔ HẤP GIẢM OXY MÁU ĐƯỢC THÔNG KHÍ NHÂN TẠO XÂM NHẬP TRONG CÁC ĐƠN VỊ HỒI SỨC TÍCH CỰC

Abstract

Objective: Describe the clinical and paraclinical characteristics of patients with hypoxemic respiratory failure receiving invasive mechanical ventilation in intensive care units (ICUs). Methods: Multicenter prospective cross-sectional study was carried out on 72 patients with invasive mechanical ventilation in three ICU departments in three hospitals from November 1, 2022 to November 30, 2022. Background pathological characteristics, ventilator settings and complications during mechanical ventilation, blood gases and the extent of lung damage on X-ray were collected and analyzed with Mann Whitney U test and Fisher' Exact test. Results: The rate of hypoxemic respiratory failure was 57.9%, 83.7% of the  comorbidities were diabetes (25.6% vs. 6.9%, p < 0.05) and the tidal volume was set lower (p < 0.05) however, the positive end-expiratory pressure, peak pressure and plateau pressure, and respiratory rate were higher than those in the non-hypoxemic group, 71.1% had organ dysfunction and more organ failure than those in the non-hypoxemic group. Patients with hypoxemic respiratory failure had lower PaO2, PaO2/FiO2, higher lactate and more lesions on chest X-ray than those in the non-hypoxemic group. Conclusion: Patients with hypoxemic respiratory failure who underwent invasive mechanical ventilation have a high rate of organ dysfunction and lung injury.