XÁC ĐỊNH MỐI TƯƠNG QUAN GIỮA TỶ SỐ ĐƯỜNG KÍNH TĨNH MẠCH CHỦ DƯỚI VÀ ĐƯỜNG KÍNH ĐỘNG MẠCH CHỦ BỤNG VỚI HEMATOCRIT, LACTATE MÁU VÀ MỐI LIÊN QUAN CỦA TỶ SỐ NÀY VỚI CÁC MỨC ĐỘ CỦA SỐT XUẤT HUYẾT DENGUE NẶNG Ở TRẺ EM TẠI BỆNH VIỆN SẢN NHI KIÊN GIANG

Abstract

Background: Dengue fever is an acute infectious disease caused by the Dengue virus, which can lead to large-scale outbreaks. The disease progresses unpredictably and can be severe, with a high mortality rate if not promptly diagnosed and treated. Ultrasound measurement of the inferior vena cava to abdominal aorta diameter ratio is useful in assessing hemodynamic status and guiding fluid resuscitation in Dengue fever management. Objectives: To describe the clinical characteristics, evaluate treatment outcomes, and determine the correlation between the the inferior vena cava to abdominal aorta diameter ratio and hematocrit, blood lactate levels, as well as its association with different severity levels of severe Dengue fever. Materials and methods: Report on a series of of pediatric patients diagnosed with severe Dengue fever who were treated at the Pediatric Intensive Care Unit, Kien Giang Obstetrics and Pediatrics Hospital. Results: A total of 18 pediatric patients meeting the inclusion criteria were enrolled. Males accounted for the majority (72,2%), with a male-to-female ratio of approximately 2,6/1. Children aged >9–15 years constituted 72,2% of cases. Dengue shock syndrome was the most common presentation (55,6%). Capillary refill time (CRT) >2 seconds was the predominant clinical sign in children with severe Dengue fever. About 1/5 of cases experienced shock recurrence, and all patients survived. A moderate inverse correlation was observed between the inferior vena cava to abdominal aorta diameter ratio and hematocrit levels, with a lower inferior vena cava to abdominal aorta diameter ratio in the severe Dengue shock syndrome group compared to the Dengue shock syndrome group. Conclusion: Severe Dengue fever predominantly affects male children aged >9–15 years. The inferior vena cava to abdominal aorta diameter ratio is lower in the severe Dengue shock syndrome group compared to the Dengue shock syndrome group and exhibits an inverse correlation with hematocrit levels in pediatric patients with severe Dengue fever.