NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG U TUYẾN DỊCH NHẦY BUỒNG TRỨNG ÁC TÍNH

Abstract

Background: Mucinous ovarian tumors are the second most common subtype of epithelial ovarian tumors, accounting for approximately 10–15% of all cases. The prognostic factors associated with recurrence in malignant mucinous ovarian tumors remain controversial due to limited studies and inconsistent findings.Objective: To describe the clinical characteristics of malignant mucinous ovarian tumors treated at Tu Du Hospital. To determine the recurrence rate and identify factors associated with recurrence in these tumors. Methods: A retrospective cohort study was conducted. Results: With a follow-up period of 60 months, the overall recurrence rate of malignant mucinous ovarian tumors was 6.45% (95% CI: 3.89–11.66). Factors significantly associated with increased recurrence risk included: Tumor rupture during surgery, which was associated with a 4.70-fold higher risk of recurrence (95% CI: 1.06–20.81; p < 0.05); Advanced FIGO stage (III or higher), which increased the risk of recurrence by 7.91 times compared to stage I (95% CI: 1.56–40.02; p < 0.05). Interestingly, for each 1 cm increase in tumor size, the risk of recurrence decreased by 67% (HR = 0.33; 95% CI: 0.12–0.93; p < 0.05). Conclusion: Patients with malignant mucinous ovarian tumors should be carefully counseled and closely monitored, especially those with intraoperative tumor rupture or advanced-stage disease (FIGO stage III or higher), as they present a higher risk of recurrence. Notably, smaller tumor size was paradoxically associated with increased risk of recurrence.