SO SÁNH ĐỘ AN TOÀN VÀ HIỆU QUẢ CỦA PHẪU THUẬT NỘI SOI MỘT LỖ VÀ NHIỀU LỖ TRONG ĐIỀU TRỊ THAI NGOÀI TỬ CUNG TẠI BỆNH VIỆN HÙNG VƯƠNG

Abstract

Introduction: Gestational diabetes mellitus (GDM) is a common metabolic disorder during pregnancy [1], with an increasing trend and significant health impacts on both mother and fetus [3, 7,8]. Nutritional therapy is the cornerstone of treatment [10], but the optimal regimen needs identification. Hung Vuong Hospital currently applies a standard dietary restriction [2] and aims to compare its effectiveness with a diet supplemented with a low-GI product [3, 4]. Objective: To compare the effectiveness of glycemic control and tolerability between standard dietary restriction and dietary restriction supplemented with Navie Cerna in GDM patients. Methods: A prospective cohort study was conducted on 160 newly diagnosed GDM pregnant women undergoing inpatient treatment at Hung Vuong Hospital from February 2023 to February 2024. Patients were divided into two groups: standard dietary restriction (n=80) and supplemented dietary restriction (n=80). Capillary blood glucose was monitored 4 times daily for 7 days. Data were analyzed using Stata. Results: The overall glycemic stability rate was 84.4%. The standard restriction group had a higher stability rate (88.8%) compared to the supplemented group (80.0%). Kaplan-Meier analysis indicated a higher probability of maintaining stability over time in the supplemented group. The supplemented group experienced higher rates of nausea (37.5% vs 28.8%) and vomiting (13.8% vs 8.8%). Gestational age was an independent predictor affecting glycemic stability (HR=1.121, p<0.001). Conclusion: Both dietary regimens are effective in managing glycemia in GDM. The standard dietary restriction provides better stability, while the supplemented diet offers better initial energy supply and a higher probability of maintaining stability over time, despite slightly higher rates of gastrointestinal symptoms