KHẢO SÁT THỰC TRẠNG SỬ DỤNG THUỐC TRONG ĐIỀU TRỊ ĐỘT QUỴ TẠI BỆNH VIỆN ĐA KHOA THỐNG NHẤT ĐỒNG NAI NĂM 2024

Abstract

Background: Stroke is one of the leading causes of mortality worldwide and in Vietnam. Therefore, pharmacological management plays a crucial role in improving quality of life and reducing the risk of recurrence in stroke patients. Objectives: To investigate the current status of drug utilization in the treatment of stroke at Thong Nhat General Hospital, Dong Nai (TNGH-DN) in 2024. Subjects and Methods: A cross-sectional descriptive study based on retrospective analysis of electronic prescriptions from stroke patients who met the inclusion criteria at TNGH-DN in 2024. Results: The study reviewed 1.696 stroke patients, including 1.587 outpatient episodes and 967 inpatient episodes. The mean age was 64,30 ± 11,92 years, and the male-to-female ratio was 1,42:1. Post-stroke sequelae were observed in 54,61% of patients.In outpatient treatment, 48,40% of patients received monotherapy regimens, with clopidogrel being the most frequently prescribed agent (89,58%). In inpatient settings, 42,91% of patients received combination therapy, with clopidogrel + acetylsalicylic acid being the predominant regimen (99,51%).Prescription analysis of 1.587 outpatient episodes (9.694 prescribed drugs) showed an average of 6,10 ± 2,58 drugs per prescription; 48,45% included vitamins, 2,00% included antibiotics, and 3,00% included injectable medications.In 967 inpatient episodes (60.978 prescribed drugs), the average number of drugs per prescription was 12,63 ± 7,46; 68,25% included vitamins, 21,92% included antibiotics, and 66,18% included injectable medications. Conclusion: The study highlights the preference for antiplatelet agents (clopidogrel) in outpatient care and the frequent use of clopidogrel + acetylsalicylic acid combination in inpatient treatment. Continuous monitoring and trend evaluation of prescription indicators are necessary to optimize pharmacotherapy outcomes.