KHẢO SÁT CHẤT LƯỢNG CUỘC SỐNG VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN MẮC PEMPHIGUS VULGARIS

Abstract

Objective: To assess the quality of life and associated factors in patients with pemphigus vulgaris. Subjects and Methods: A descriptive case series was conducted on 34 patients diagnosed with pemphigus vulgaris who attended the Ho Chi Minh City Hospital of Dermatology and Venereology from February to October 2023. Results: The mean DLQI score was 9.86 ± 6.94, with 91.2% of patients reporting varying degrees of impaired quality of life. Decreased quality of life was significantly associated with pruritus (p = 0.029), mucosal involvement (p = 0.048), and higher disease severity (PDAI >15; p = 0.002). No significant associations were found between DLQI scores and age, gender, occupation, disease duration, or treatment modality. Conclusion: Pemphigus vulgaris significantly impairs patients' quality of life, particularly in those with pruritus, mucosal lesions, and severe disease. Routine quality-of-life assessment should be integrated into clinical management to optimize patient care outcomes.