EFFECTIVENESS OF RADIOTHERAPY ALONE AND CONCURRENT CHEMORADIOTHERAPY IN PATIENTS WITH NASOPHARYNGEAL CARCINOMA

Tần Phạm Huy, Ngọc Dương Thế

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Abstract

Objectives: To evaluate the therapeutic effectiveness of radiotherapy alone and concurrent chemoradiotherapy in patients with nasopharyngeal carcinoma. Subjects: A total of 119 patients diagnosed and treated for nasopharyngeal carcinoma at the National Cancer Hospital and Hanoi Medical University Hospital from 2013 to 2016. Methods: A longitudinal descriptive study with treatment regimens including radiotherapy alone and concurrent chemoradiotherapy using cisplatin. Results: Concurrent chemoradiotherapy was the most common treatment method (54.6%), with concurrent chemoradiotherapy using cisplatin accounting for the highest proportion (32.8%), followed by neoadjuvant chemotherapy combined with concurrent chemoradiotherapy at 13.4%, and neoadjuvant chemotherapy combined with radiotherapy at the lowest rate of 8.4%. Radiotherapy alone constituted a smaller proportion (45.4%). Most patients achieved a complete response to treatment (74.0%), 23.5% of patients had a partial response, and only 2.5% of patients showed no response to treatment. Conclusion: Both radiotherapy alone and concurrent chemoradiotherapy are effective treatment approaches for patients with nasopharyngeal carcinoma. Applying these methods at the appropriate disease stage, selecting the right treatment approach, and adhering to the prescribed protocol can optimize disease control, improve the complete response rate, and enhance long-term survival prospects for patients.

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References

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