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ANALYSIS OF KIDNEY STONE COMPOSITION BY URINE PH AND HOUNSFIELD UNITS ON CT SCAN
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Abstract
Objective: Assessment of the correlation between renal stone composition with urine pH and hounsfield units on CT scan. Subjects and Methods: Patients undergoing kidney stone surgery at the specialized kidney stone treatment department of Binh Dan Hospital who agreed to participate in the study were included. The prospective study described a series of cases from July 2023 to August 2024. Results: Over a 13-month period, we collected 450 stone units (from 442 patients). The standardized residuals were 5.06 for uric acid stones in an acidic urine pH and -2.33 in a neutral urine pH, -2.08 for struvite stones in a neutral to slightly acidic urine pH, and 2.33 for weddellite stones in an alkaline urine pH. Statistically significant differences in Hounsfield Units (HU) were observed among specific stone groups, namely uric acid stones (P = 0.00007), struvite stones (P = 0.048), and whewellite stones (P = 0.033). The areas under the receiver operating characteristic (ROC) curve based on HU for whewellite, struvite, and uric acid stones were 0.575, 0.675, and 0.838, respectively. Conclusion: Uric acid stones exhibited a tendency to occur in an acidic urine environment. Weddellite stones were observed to occur more frequently in an alkaline urine environment. Struvite stones showed a reduced tendency to occur in neutral to slightly acidic urine environments. The Hounsfield Units of uric acid, struvite, and whewellite stones demonstrated statistically significant differences compared to other stone types.
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Keywords
kidney stone, stone analysis, urine pH, Hounsfield
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