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EFFECTIVENESS OF APPLYING THE WHO GUIDELINE “DOING WHAT MATTERS IN TIMES OF STRESS” ON CORONARY ARTERY DISEASE PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
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Abstract
Background: Patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) are at increased risk of psychological disorders such as stress and depression, which negatively impact clinical outcomes and quality of life. The World Health Organization (WHO) guideline "Doing What Matters in Times of Stress" is a short-term psychological intervention shown to alleviate mental distress. Objective: To evaluate the effectiveness of the WHO guideline "Doing What Matters in Times of Stress" in reducing stress and depression among CAD patients after PCI. Subjects and Methods: A quasi-experimental study with a control group was conducted on 98 CAD patients undergoing CTĐMVQD at Military Hospital 175 from June 2024 to May 2025. Patients were divided into two groups: the intervention group received psychological guidance following WHO recommendations, while the control group received standard care. Stress and depression were assessed using the PSS-10 and PHQ-9 scales post-CTĐMVQD and after one month. Results: The mean age of participants was 64.33 ± 10.25 years, with 59.18% being male. The prevalence of hypertension, diabetes mellitus, and dyslipidemia was high in both groups. After one month, the intervention group showed a significant reduction in PHQ-9 scores from 2.69 ± 1.34 to 0.87 ± 1.09 (p<0.001) and in PSS-10 scores from 18.26 ± 0.31 to 16.10 ± 0.19 (p<0.001). The control group showed a milder decrease in PHQ-9 from 3 ± 1.69 to 1.89 ± 1.08 and in PSS-10 from 17.97 ± 1.87 to 17.08 ± 1.44. Conclusion: The WHO guideline "Doing What Matters in Times of Stress" is an effective intervention that helps reduce stress and depression in CAD patients after PCI.
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Keywords
WHO, stress, depression, PCI, psychological intervention
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