ANALYSIS OF RENAL STONE COMPOSITION ACCORDING TO CERTAIN METABOLIC DISEASES

Chiến Nguyễn Xuân, Toàn Đỗ Anh, Thuấn Nguyễn Đạo, Khôi Lê Trọng, Thái Nguyễn Ngọc, Khoa Nguyễn Văn, Thống Phan Thành, Hoàng Nguyễn Thái

Main Article Content

Abstract

Objective: Assessment of the association between kidney stone composition and certain metabolic disorders. Subjects and Methods: Patients undergoing kidney stone surgery at the specialized kidney stone treatment department of Binh Dan Hospital who agreed to participate in the study were included. The prospective study described a series of cases from July 2023 to August 2024. Results: Over a 13-month period, we collected 450 stone samples from 442 patients. The prevalence of diabetic patients by stone type was: whewellite 18.03%, weddellite 10.71%, hydroxyapatite 17.70%, uric acid 33.33%, and struvite 11.76%. The prevalence of hypertensive patients by stone type was: whewellite 28.33%, weddellite 32.14%, hydroxyapatite 29.20%, uric acid 19.05%, and struvite 41.18%. The mean BMI for all patients was 23.49 ± 3.25, mean BMI (male): 23.25 ± 2.99, mean BMI (female): 23.83 ± 3.56. Conclusion: There was no statistically significant association between kidney stone composition and common metabolic factors such as diabetes mellitus, hypertension, and overweight-obesity.

Article Details

References

1. Lang J, Narendrula A, El-Zawahry A, Sindhwani P, Ekwenna O. Global Trends in Incidence and Burden of Urolithiasis from 1990 to 2019: An Analysis of Global Burden of Disease Study Data. Eur Urol Open Sci. Jan 2022;35:37-46. doi:10.1016/j.euros.2021.10.008
2. Kadlec AO, Greco K, Fridirici ZC, Hart ST, Vellos T, Turk TM. Metabolic syndrome and urinary stone composition: what factors matter most? Urology. Oct 2012;80(4):805-10. doi:10.1016/j.urology.2012.05.011
3. Daudon M, Traxer O, Conort P, Lacour B, Jungers P. Type 2 diabetes increases the risk for uric acid stones. J Am Soc Nephrol. Jul 2006;17(7): 2026-33. doi:10.1681/asn. 2006030262
4. Marchini GS, Sarkissian C, Tian D, Gebreselassie S, Monga M. Gout, stone composition and urinary stone risk: a matched case comparative study. J Urol. Apr 2013;189(4): 1334-9. doi:10.1016/j.juro.2012.09.102
5. Pan WH, Yeh WT. How to define obesity? Evidence-based multiple action points for public awareness, screening, and treatment: an extension of Asian-Pacific recommendations. Asia Pac J Clin Nutr. 2008;17(3):370-4.
6. Wang D, Tan J, Geng E, et al. Impact of body mass index on size and composition of urinary stones: a systematic review and meta-analysis. Int Braz J Urol. May-Jun 2023;49(3):281-298. doi:10.1590/s1677-5538.Ibju.2022.0587
7. Wen W, Li Y, Chen Q, Li J. Serum and urine uric acid level may have different predictive value for urinary stone composition: a retrospective cohort study of 718 patients in Chinese population. Int Urol Nephrol. Sep 2022;54(9): 2247-2254. doi:10.1007/s11255-022-03121-8
8. Margaret S. Pearle MD P, Jodi A. Antonelli MD, Yair Lotan MD. Etiology, Epidemiology, and Pathogenesis. Campbell-Walsh Urology. 12 ed. Elsevier; 2020:9252-9405:chap 91.
9. Daudon M, Bouzidi H, Bazin D. Composition and morphology of phosphate stones and their relation with etiology. Urol Res. Dec 2010; 38(6):459-67. doi:10.1007/s00240-010-0320-3
10. Bijelic R, Milicevic S, Balaban J. Incidence of osteoporosis in patients with urolithiasis. Med Arch. Oct 2014;68(5):335-8. doi:10.5455/ medarh.2014.68.335-338