ANALYSIS OF RENAL STONE COMPOSITION ACCORDING TO CERTAIN METABOLIC DISEASES
Main Article Content
Abstract
Objective: Assessment of the association between kidney stone composition and certain metabolic disorders. Subjects and Methods: Patients undergoing kidney stone surgery at the specialized kidney stone treatment department of Binh Dan Hospital who agreed to participate in the study were included. The prospective study described a series of cases from July 2023 to August 2024. Results: Over a 13-month period, we collected 450 stone samples from 442 patients. The prevalence of diabetic patients by stone type was: whewellite 18.03%, weddellite 10.71%, hydroxyapatite 17.70%, uric acid 33.33%, and struvite 11.76%. The prevalence of hypertensive patients by stone type was: whewellite 28.33%, weddellite 32.14%, hydroxyapatite 29.20%, uric acid 19.05%, and struvite 41.18%. The mean BMI for all patients was 23.49 ± 3.25, mean BMI (male): 23.25 ± 2.99, mean BMI (female): 23.83 ± 3.56. Conclusion: There was no statistically significant association between kidney stone composition and common metabolic factors such as diabetes mellitus, hypertension, and overweight-obesity.
Keywords
kidney stone, urinary stone analysis, metabolic disease, hypertension, diabetes mellitus, gout
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References
2. Kadlec AO, Greco K, Fridirici ZC, Hart ST, Vellos T, Turk TM. Metabolic syndrome and urinary stone composition: what factors matter most? Urology. Oct 2012;80(4):805-10. doi:10.1016/j.urology.2012.05.011
3. Daudon M, Traxer O, Conort P, Lacour B, Jungers P. Type 2 diabetes increases the risk for uric acid stones. J Am Soc Nephrol. Jul 2006;17(7): 2026-33. doi:10.1681/asn. 2006030262
4. Marchini GS, Sarkissian C, Tian D, Gebreselassie S, Monga M. Gout, stone composition and urinary stone risk: a matched case comparative study. J Urol. Apr 2013;189(4): 1334-9. doi:10.1016/j.juro.2012.09.102
5. Pan WH, Yeh WT. How to define obesity? Evidence-based multiple action points for public awareness, screening, and treatment: an extension of Asian-Pacific recommendations. Asia Pac J Clin Nutr. 2008;17(3):370-4.
6. Wang D, Tan J, Geng E, et al. Impact of body mass index on size and composition of urinary stones: a systematic review and meta-analysis. Int Braz J Urol. May-Jun 2023;49(3):281-298. doi:10.1590/s1677-5538.Ibju.2022.0587
7. Wen W, Li Y, Chen Q, Li J. Serum and urine uric acid level may have different predictive value for urinary stone composition: a retrospective cohort study of 718 patients in Chinese population. Int Urol Nephrol. Sep 2022;54(9): 2247-2254. doi:10.1007/s11255-022-03121-8
8. Margaret S. Pearle MD P, Jodi A. Antonelli MD, Yair Lotan MD. Etiology, Epidemiology, and Pathogenesis. Campbell-Walsh Urology. 12 ed. Elsevier; 2020:9252-9405:chap 91.
9. Daudon M, Bouzidi H, Bazin D. Composition and morphology of phosphate stones and their relation with etiology. Urol Res. Dec 2010; 38(6):459-67. doi:10.1007/s00240-010-0320-3
10. Bijelic R, Milicevic S, Balaban J. Incidence of osteoporosis in patients with urolithiasis. Med Arch. Oct 2014;68(5):335-8. doi:10.5455/ medarh.2014.68.335-338