CLINICAL AND PARA-CLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES OF COMMUNITY-ACQUIRED PNEUMONIA PATIENTS REQUIRING INVASIVE VENTILATION AT DUC GIANG GENERAL HOSPITAL

Linh Phạm Thùy, Hoa Nguyễn Phương, Oanh Trần Thị

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Abstract

Objective: Describe the clinical and para-clinical characteristics and treatment outcomes of patients with community-acquired pneumonia requiring invasive mechanical ventilation at Duc Giang General Hospital. Methods: A descriptive cross-sectional study was conducted on 42 patients with community-acquired pneumonia requiring invasive mechanical ventilation, treated at Duc Giang General Hospital from August 2024 to April 2025. Results: 88,1% of patients were aged 65 years or older, male/female ratio was 2,8; 38,9% smoked and 11,9% were alcoholics. Chronic comorbidities: cardiovascular disease 59,5%, stroke 28,6%. Common respiratory symptoms were dyspnea 90,5%, cough 81,0%, crackles 92,9%. The average white blood cell count was 15,6 ± 11,6 G/L. The average CRP concentration was 123,6 ± 96,7 mg/L. 81% of patients received a combination of 2 groups of antibiotics from the beginning. The mortality/exacerbation rate was 28,6%. Factors associated with mortality risk were septic shock, PaO2/FiO2 ≤ 250, and multilobar lung lesions (p<0,05). Conclusion: The study showed that the majority of patients were elderly, had a history of smoking and had chronic diseases: chronic respiratory disease, chronic cardiovascular disease, etc. Common clinical symptoms were fever, shortness of breath, cough, moist rales, and crackles in the lungs. The inflammatory index was high. X-rays often showed multi-lobar lung lesions. Treatment often combined two antibiotics from the beginning, but the mortality rate was still high. Factors such as septic shock, PaO2/FiO2 ≤ 250 and multi-lobar lung lesions increased the risk of death in patients.

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