ĐẶC ĐIỂM LÂM SÀNG COVID-19 Ở BỆNH NHÂN LỌC MÁU TẠI BỆNH VIỆN ĐẠI HỌC Y DƯỢC THÀNH PHỐ HỒ CHÍ MINH

Abstract

Objective: To describe clinical characteristics, laboratory data and early outcome of hospitalized COVID-19 patients with hemodialysis at the University Medical Center, Ho Chi Minh City. Method: We conducted a retrospective observational study from July 2021 to July 2022 to record data about patients with hemodialysis hospitalized due to COVID-19, diagnosed by RT-PCR. Descriptive statistics, chi-square test, logistic regression were performed in the statistical analysis. Results: Our study enrolled 56 patients with a mean age of 62.89 ± 2 years, with a female-to-male ratio of 1:1. The most frequently reported clinical symptoms were fever (60.7%), cough (66.3%), shortness of breath (50%). Among the 56 patients, 25 patients (44.6%) were classified as severe or critical degree, 8 patients (14.3%) died and 48 patients (85.7%) were able to be discharged within the observation period. The factors related to severity of COVID-19 include age over 60, diabetes, respiratory failure at presentation. Various laboratory parameters have been related with adverse outcomes. These encompass lymphopenia, elevated levels of LDH, interleukin-6, CRP, and procalcitonin. Moreover, we also find out protective factors including complete vaccination and good nutritional status of the patients. Conclusion: Our findings suggest that COVID-19 infection in hemodialysis patients increases the risk of mortality and poor prognosis. The risk of death and severity rises with age, comorbidities, respiratory failure, and elevated inflammatory markers at onset.