GIÁ TRỊ CỦA SINH THIẾT KIM LÕI DƯỚI HƯỚNG DẪN SIÊU ÂM TRONG CHẨN ĐOÁN U SAU PHÚC MẠC Ở TRẺ EM

Abstract

Objective: This study was to evaluate the diagnostic value of ultrasound-guided core needle biopsy (CNB) for pediatric retroperitoneal tumors and the complications related to procedure. Subjects and Methods: the study was conducted on 110 children diagnosed with retroperitoneal tumor underwent CNB at the Vietnam National Children’s Hospital from July 2024 to April 2025. Evaluated parameters including general characteristics, imaging features, pathological results, adverse event features. Results: Overall biopsy adequacy rate (defined as sufficient to make a diagnosis) was 99.1%. There were 7 benign tumors, and 102 malignant tumors. In determining malignant lesions, CNB showed a sensitivity of 97.1%, a specificity of 100%, an accuracy of 97.2%. Forty-five patients underwent surgery, needle biopsy and surgery had high concordance in histopathological diagnosis (Kappa coefficient = 0.63). There were 6 cases (5.4%) of post procedure complications, of which one severe bleeding requiring blood transfusion accounting for 0.9%. Conclusion: Ultrasound-guided core needle biopsy is a minimally invasive, safe and accurate technique for histopathological diagnosis and genetic biology, with a low rate of complications, it can replace surgical biopsy in the diagnosis of retroperitoneal tumors in children.