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Date Published: 16/09/2025
Abstract Views: 138
Views pdf: 113
DOI: https://doi.org/10.51298/vmj.v553i2.15419
Issue
Vol. 553 No. 2 (2025)
Section
Các bài báo
How to Cite
Trần Thiên, T., Hoàng Thị, L., Lê Đình, T., Lê Thị Tuyết, L., & Nguyễn Như, V. (2025). MỐI LIÊN QUAN GIỮA KIỂU MẪN CẢM DỊ NGUYÊN VỚI ĐẶC ĐIỂM LÂM SÀNG VÀ HIỆU QUẢ ĐIỀU TRỊ Ở BỆNH NHÂN HEN PHẾ QUẢN TẠI THÀNH PHỐ HỒ CHÍ MINH. Vietnam Medical Journal, 553(2). https://doi.org/10.51298/vmj.v553i2.15419

MỐI LIÊN QUAN GIỮA KIỂU MẪN CẢM DỊ NGUYÊN VỚI ĐẶC ĐIỂM LÂM SÀNG VÀ HIỆU QUẢ ĐIỀU TRỊ Ở BỆNH NHÂN HEN PHẾ QUẢN TẠI THÀNH PHỐ HỒ CHÍ MINH

Tài Trần Thiên, Lâm Hoàng Thị, Tùng Lê Đình, Lan Lê Thị Tuyết, Vinh Nguyễn Như

Main Article Content

Abstract

Objective: To evaluate the association between allergen sensitization patterns with clinical characteristics and treatment outcomes in asthmatic patients. Methods: A cross-sectional, prospective study was conducted on 146 asthmatic patients in Ho Chi Minh City. Skin prick testing with 12 allergens, clinical assessment according to GINA, ACT score, and pulmonary function tests were performed. Allergen avoidance counseling intervention was implemented for 3 months. Results: The prevalence of mono-sensitization was 56.2% and poly-sensitization was 43.8%. The poly-sensitized group was younger (38.02±12.65 vs 42.82±13.54), had earlier onset (21.16±12.26 vs 33.41±15.03), higher uncontrolled asthma rate (65.45% vs 23.17%), lower FEV1, and more frequent reliever use (p<0.001). Allergen avoidance counseling significantly improved outcomes in the mono-sensitized group (77.78% achieved complete control) but showed limited efficacy in the poly-sensitized group. Conclusion: Sensitization patterns influence asthma severity and treatment response, necessitating differentiated treatment strategies.

Article Details

Keywords

Asthma, mono-sensitization, poly-sensitization, skin prick test, allergen avoidance, asthma control

References

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