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Date Published: 18/09/2025
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DOI: https://doi.org/10.51298/vmj.v553i2.15423
Issue
Vol. 553 No. 2 (2025)
Section
Các bài báo
How to Cite
Trần Doanh, H., Lê Thanh, S., Trần Ngọc, D., & Bùi Khắc, C. . (2025). CORRELATION BETWEEN P-AMPKΑ EXPRESSION, BLOOD BIOCHEMICAL INDICATORS, AND SURVIVAL OUTCOMES IN GASTRIC CANCER SURGERY PATIENTS. Vietnam Medical Journal, 553(2). https://doi.org/10.51298/vmj.v553i2.15423 (Original work published September 16, 2025)

CORRELATION BETWEEN P-AMPKΑ EXPRESSION, BLOOD BIOCHEMICAL INDICATORS, AND SURVIVAL OUTCOMES IN GASTRIC CANCER SURGERY PATIENTS

Hiệu Trần Doanh, Sơn Lê Thanh, Dũng Trần Ngọc, Cường Bùi Khắc

Main Article Content

Abstract

Objective: To evaluate the relationship between tissue expression of p-AMPKα and blood biochemical indices as well as postoperative survival time in patients with gastric carcinoma. Methods: A descriptive longitudinal study was conducted on 68 patients with gastric carcinoma who underwent curative surgery. The expression of p-AMPKα in tissue was assessed using immunohistochemistry with antibodies from Cell Signaling Technology. Results: Serum albumin levels were significantly higher in the p-AMPKα positive group compared to the negative group (p = 0.023). The concentrations of CEA, CA19.9, and CA72.4 tended to be higher in patients with negative p-AMPKα expression, although the differences were not statistically significant (p > 0.05). Postoperative survival time and cumulative survival rates showed no statistically significant differences between the p-AMPKα negative and positive groups. Conclusion: The p-AMPKα positive group had significantly higher serum albumin levels than the negative group. No statistically significant differences were observed in survival time or cumulative survival rates between the two groups.

Article Details

Keywords

Gastric carcinoma, p-AMPKα, biochemical indices, overall survival

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