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Date Published: 05/01/2022
Abstract Views: 255
Views PDF: 176
DOI: https://doi.org/10.51298/vmj.v508i1.1549
Issue
Vol. 508 No. 1 (2021)
Section
Các bài báo
How to Cite
Công Hoàng, N. ., & Công Định, Đinh . (2022). 5 YEARS COSMETIC OUTCOME AFTER INTENSITY MODULATED RADIATION THERAPY FOLLOWED CONSERVATIVE SURGERY OF BREAST CANCER STAGE I-II AT K HOSPITAL. Vietnam Medical Journal, 508(1). https://doi.org/10.51298/vmj.v508i1.1549

5 YEARS COSMETIC OUTCOME AFTER INTENSITY MODULATED RADIATION THERAPY FOLLOWED CONSERVATIVE SURGERY OF BREAST CANCER STAGE I-II AT K HOSPITAL

Nguyễn Công Hoàng1,, Đinh Công Định1
1 K Hospital

Main Article Content

Abstract

Breast cancer is the most common cancer in women. While conservative treatment is indicated for early stage breast cancer (stage I-II), adjuvant radiation therapy is mandatory. Forward intensity modulated radiotherapy (F-IMRT) is a modern radiation technique by using LINAC with multileaf collimator system to optimize radiation treatment plan in order to improve homogeneity of PTV, minimizing the dose to organ at risks. Our study aims to review clinical features and 5 years cosmetic outcome after F-IMRT followed breast cancer conservative treatment of at K hospital. Objectives and methods: 68 eligible patients with stage I-II breast cancer were selected, treated by forward IMRT followed conservative surgery from 2/2016 to 10/2021 at K Hospital. Review clinical features and estimate cosmetic outcome at the end of 5 years postoperative radiotherapy. Result: Clinical features of 68 eligible patients: median age is 44; the lowest is 21; tumor location: left breast accounted for 61.2%, upper outer quadrant of the breast is most common (64.2%). TNM stage: mostly stage I-IIA (91.2%); Breat volume: most patients with small and average breast volume (90.3%). The 5-year disease-free survival (DFS)  rates are 92.6%. The 5- years overall survival (OS) rates is 95.6%. Quality of cosmetic outcome account for 80.2% (Excellent: 37.6%; Good: 20.8%; Fair: 21.8%). Conclusion: In our study, the 5-year disease-free survival was 92.6%, the 5-year overall survival was 95.6%. we found that high rate of fair, good and excellent cosmetic result group reached 80.2%. The side effects of radiation therapy that affect cosmetic results often occur late, so long-term follow-up after treatment is required for more accurate conclusions.

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References

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