MỘT SỐ ĐẶC ĐIỂM RỐI LOẠN NHẬN THỨC Ở BỆNH NHÂN ĐỘNG KINH SAU ĐỘT QUỴ

Abstract

Objective: To evaluate cognitive impairment characteristics and associated factors in patients with post-stroke epilepsy (PSE). Subjects and Methods: The study included patients diagnosed with post-stroke epilepsy who were managed and treated at the Department of Neurology, 108 Military Central Hospital, and the Neurology Center, Bach Mai Hospital, from August 2024 to July 2025. This was a prospective, cross-sectional descriptive study with convenience sampling. Results: From August 2024 to July 2025, 52 patients with post-stroke epilepsy were included, of whom 69.2% were male. The mean age was 63.6 ± 16.4 years (range: 16–86 years), and ischemic stroke accounted for 63.5% of cases. Cognitive impairment was observed in 67.3% of patients, with mild neurocognitive disorder in 46.2% and major neurocognitive disorder in 21.1%. Verbal memory impairment was present in 59.6% of patients, visuospatial memory impairment in 57.7%, and visual memory impairment in 44.2%. Language deficits were found in 34.6%, attention deficits in 26.9%, and executive dysfunction in 19.2%. Cognitive impairment was significantly associated with older age, hemorrhagic stroke, frontal and temporal lobe lesions, and involvement of two or more brain regions. Conclusion: Cognitive impairment is common in patients with post-stroke epilepsy (67.3%), with the highest prevalence observed in verbal memory impairment (59.6%) and visuospatial-temporal memory impairment (57.7%). Patients aged ≥60 years, those with hemorrhagic stroke, frontal and temporal lobe involvement, or ≥2 affected brain regions are at higher risk and should be carefully assessed for cognitive dysfunction.