KHẢO SÁT CHỨC NĂNG THẬN CỦA NGƯỜI BỆNH CÓ NGUY CƠ CAO TẠI BỆNH VIỆN ĐẠI HỌC Y HÀ NỘI NĂM 2024

Abstract

Objective: This study aimed to evaluate the urinary albumin-to-creatinine ratio (uACR), estimated glomerular filtration rate (eGFR), and describe several factors associated with renal function in high-risk patients at Hanoi Medical University Hospital. Methods: A cross-sectional descriptive study was conducted on 428 patients identified as high-risk for chronic kidney disease (CKD) at Hanoi Medical University Hospital. Results: The mean age of the study population was 58.58 ± 13.21 years, with 54.2% being male. The prevalence of overweight and obesity was 43.7%. The distribution of uACR levels was as follows: <30 mg/g in 71.0% of patients, 30–300 mg/g in 27.4%, and >300 mg/g in 1.6%. According to KDIGO risk stratification, the proportions of patients at moderate, high, and very high risk of CKD were 24.1%, 5.1%, and 1.9%, respectively. Factors statistically significantly associated with impaired kidney function included eGFR, body mass index (BMI), hypertension, family history of kidney disease, and the use of antihypertensive medications, insulin, and statins. Conclusion: The urinary albumin-to-creatinine ratio (uACR) serves as an effective, simple, and feasible screening tool for the early detection of kidney damage in high-risk individuals, even when eGFR remains within normal limits or is only mildly decreased. The combined use of uACR and eGFR can enhance early diagnosis, facilitate risk stratification, and optimize management strategies for patients at risk of chronic kidney disease.