ASSOCIATION BETWEEN THE FIBROSIS-4 INDEX AND SELECTED CLINICAL AND PARACLINICAL FEATURES IN PATIENTS ADMITTED WITH ACUTE HEART FAILURE

Thế Dũng Bùi, Kim Trang Trần, Thị Diễm Kiều Phạm, Anh Kiệt Huỳnh, Thị Hồng Thơ Lê

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Abstract

Objective: To evaluate the association between the FIB-4 index and clinical as well as paraclinical characteristics in hospitalized patients with acute heart failure. Methods: A cross-sectional descriptive study was conducted on 349 patients aged ≥18 years who were hospitalized for acute heart failure at the Department of Cardiology, University Medical Center Ho Chi Minh City from March 2024 to March 2025. Results: Mean age, prevalence of atrial fibrillation, AST, ALT, NT-proBNP levels, and pulmonary artery pressure increased progressively across FIB-4 groups (p < 0.05). Conversely, BMI and platelet count decreased in patients with higher FIB-4 scores. No significant differences were observed in left ventricular ejection fraction or serum sodium levels among the groups. A high FIB-4 score reflected greater disease severity and multi-organ involvement. Conclusion: The FIB-4 index is closely associated with clinical and paraclinical parameters in patients hospitalized with acute heart failure. It serves as a simple marker for risk screening and stratification, supporting optimal assessment and management of these patients.

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References

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