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THE TREATMENT PROGNOSIS OF NLR AND PLR INDEXES IN HEPATOCELLULAR CARCINOMA AT 103 MILITARY HOSPITAL
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Abstract
Objective: Assesing the treatment prognosis of NLR, PLR indexes in hepatocellular carcinoma patients. Subjects: Studying on 70 intermediate stages hepatocellular carcinoma undergoing Transarterial Chemoembolization (TACE) at Military Hospital 103 from April 2024 to December 2024. Methods: A retrospective descriptive, collecting the treatment output indexes and NLR, PLR indexes on the medical records. Results: The optimal threshold values of NLR and PLR to distinguish response and non-response in the study group are NLR= 2,285 and PLR = 116,67. Patients with NLR ≥ 2,285 have worse treatment respone significantly compared with the group of patients with NLR < 2,285 (p< 0,0001). Patients with PLR ≥ 116,67 have worse treatment respone significantly compared with the group of patients with PLR < 116,67 with p <0,0001. Additionally, NLR, PLR indexes are related to a number of prognostic factors, such as PS, AFP, number of tumor, tumor size. Conclusion: Pretreatment NLR and PLR index can predict response to TACE therapy in hepatocellular carcinoma patients.
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Keywords
NLR, PLR; hepatocellular carcinoma.
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