KẾT QUẢ ĐIỀU TRỊ TRẺ SƠ SINH MẮC NHIỄM KHUẨN HÔ HẤP DƯỚI CÓ NHIỄM VIRUS HỢP BÀO HÔ HẤP TẠI BỆNH VIỆN ĐA KHOA XANH PÔN

Abstract

Objective: This study aimed to describe the characteristics and treatment outcome of neonates with lower respiratory tract infections associated with respiratory syncytial virus (RSV) at Xanh Pon General Hospital. Methods: A descriptive cross-sectional study was conducted on 82 patients. The variables investigated included demographic characteristics, clinical manifestations, and subclinical findings. Results: Lower respiratory tract infections associated with RSV in neonates were more common in males than females, with a male-to-female ratio of 1.4:1; however, this difference was not statistically significant. The average time from the onset of initial symptoms to hospital admission was 2.96 ± 0.96 days. The most common manifestations included cough (100%), wheezing (80.5%), fine moist rales (97.6%), rhonchi and crackles (30.5%), and respiratory distress (53.7%). In terms of laboratory findings, white blood cell counts and CRP levels were mostly within normal limits. Chest X-rays frequently revealed patchy or diffuse opacities (63.4%), bronchial wall thickening (25.6%), and hyperinflation (15.9%). The detection rate of bacterial pathogens via culture, as well as co-detection of bacterial and viral co-infections, was relatively low. All patients recovered or improved, with 75.6% fully recovered and discharged. No patients required transfer to higher-level care or left the hospital prematurely. Conclusion: The study demonstrates that RSV-associated lower respiratory tract infections in neonates present with relatively typical clinical and subclinical characteristics, with respiratory symptoms predominating. Most hematological, microbiological, and radiological parameters remained within mild to moderate ranges. The treatment outcomes were mostly favorable, indicating the effectiveness of the current therapeutic regimen.