COMPARISON OF LLN AND FIXED RATIO FEV₁/FVC IN THE DIAGNOSIS OF OBSTRUCTIVE VENTILATORY DISORDERS AT THE PULMONARY FUNCTION UNIT, HANOI MEDICAL UNIVERSITY HOSPITAL

Thị Huệ Đỗ , Hà Trang Ngô, Thị Minh Trang Đàm, Thái Dương Hoàng, Đình Tùng Lê, Trung Sơn Nguyễn

Main Article Content

Abstract

Objective: To compare the value of the lower limit of normal (LLN) and the fixed ratio FEV1/FVC < 0.7 in diagnosing obstructive pulmonary disease at the Pulmonary Function Testing Unit, Hanoi Medical University Hospital. Subjects and methods: A cross-sectional descriptive study was conducted on 76 patients undergoing respiratory function tests at the Pulmonary Function Testing Unit R19-02, Hanoi Medical University Hospital. Results: Among male patients, the prevalence of obstructive ventilatory disorder was 42.22% using the LLN criterion, compared to 40% using the fixed ratio (FEV₁/FVC < 0.7). In female patients, the prevalence was 6.45% using both criteria. In the entire study population, the prevalence was 27.63% according to LLN and 26.32% according to the fixed ratio. Conclusion: Both LLN and the fixed ratio (FEV₁/FVC < 0.7) are valuable diagnostic criteria for obstructive ventilatory disorders. However, LLN is recommended for improved diagnostic accuracy, especially in younger male patients with fewer risk factors.

Article Details

References

3,1% người trưởng thành ở Việt Nam mắc căn bệnh là nguyên nhân gây tử vong thứ 3 trên thế giới - Bộ Y tế. Accessed November 24, 2024.
2. Townsend MC. Conflicting Definitions of Airways Obstruction. Chest. 2007;131(2):335-336. doi:10.1378/chest.06-2736
3. Vestbo J. GOLD and the fixed ratio. Int J Chron Obstruct Pulmon Dis. 2012; 7:663-665. doi:10.2147/COPD.S35769
4. Interpretative strategies for lung function tests - PubMed. Accessed March 30, 2024. https://pubmed.ncbi.nlm.nih.gov/16264058/
5. Quanjer PH, Stanojevic S, Cole TJ, et al. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012;40(6):1324-1343. doi:10.1183/09031936.00080312
6. Yewande E. Odeyemi, O'Dene Lewis, Julius Ngwa, Kristen Dodd, Richard F. Gillum, Alem Mehari, Does Low FEV1 in Addition to Fixed Ratio and/or Lower Limit of Normal of FEV1/FVC Improve Prediction of Mortality in COPD? The NHANES-III-linked-mortality Cohort, Journal of the National Medical Association, Volume 111, Issue 1,2019, Pages 94-100, ISSN 0027-9684, https://doi.org/10.1016/j.jnma.2018. 06.006.