IMAGING CHARACTERISTICS AND TREATMENT OUTCOMES OF THORACIC AND LUMBAR VERTEBRAL COMPRESSION FRACTURES IN PATIENTS AGED 20-50 YEARS USING PERCUTANEOUS VERTEBROPLASTY WITH BIOLOGICAL CEMENT UNDER DIGITAL SUBTRACTION ANGIOGRAPHY GUIDANCE

Anh Nguyễn Quang, Cảnh Đỗ Văn, Lưu Vũ Đăng

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Abstract

Objective: To evaluate the imaging characteristics of the lesions and the treatment outcomes of percutaneous vertebroplasty (PVP) using biological cement under digital subtraction angiography (DSA) guidance in patients aged 20-50 years at Ha Giang General Hospital. Subjects and Methods: A longitudinal descriptive study was conducted on 36 patients with thoracolumbar vertebral compression fractures as confirmed on X-ray and MRI. These patients underwent percutaneous vertebroplasty from January 2021 to September 2025. Post-procedural outcomes were assessed after 3 months, focusing on pain relief and recovery. Results: The male/female ratio was 25/11. The average age was 40.6 ± 6.8 years. The main locations of the fractures were the thoracolumbar junction (54%) and the lumbar region (44%). Most patients had one vertebral body fracture (66.67%). The anterior vertebral body height increased from 30.05 ± 3.47 cm before the procedure to 32.82 ± 2.76 cm after 3 months (p < 0.001). All patients underwent a single pedicle puncture technique and non-balloon method. The average volume of cement used was 4.92 ± 0.71 ml. Cement leakage into the paravertebral veins occurred in 27.78% of patients. Function and pain symptoms improved significantly after the procedure, with most patients transitioning from moderate to severe dysfunction (ODI 41-80%) to mild dysfunction (ODI 0-20%) and being classified as "good" according to MacNab criteria. Conclusion: PVP under DSA guidance is a safe and effective technique for treating thoracic and lumbar vertebral compression fractures in young patients, helping to improve vertebral body height, reduce pain, and enhance motor function.

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References

1. Jansson K å, Svedmark P, Buskens E, Larsson M, Blomqvist P, Adami J. Epidemiology of thoracolumbar spine fractures–a nationalwide study in sweden. Orthopaedic proceedings. 2009;91-b(supp_i): 22-23. doi:10.1302/0301-620X. 91BSUPP_I.0910022e
2. Wu AM, Bisignano C, James SL, et al. Global, regional, and national burden of bone fractures in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019. The Lancet Healthy Longevity. 2021;2(9): e580-e592. doi:10.1016/ S2666-7568(21)00172-0
3. Jensen ME, Evans AJ, Mathis JM, et al. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects and results. Radiology. 1997;202(1):81-86. https://doi.org/10.1148/radiology.202.1. 8988181
4. Lieberman IH, Dudeney S, Reinhardt MK, et al. Initial outcome and efficacy of kyphoplasty in the treatment of painful osteoporotic vertebral compression fractures. Spine J. 2001;1(5): 357-364. https://doi.org/ 10.1016/ S1529-9430(01) 00083-2
5. McGraw JK, Cardella JF, Barr JD, et al. Society of Interventional Radiology Quality Improvement Standards for Percutaneous Vertebroplasty. J Vasc Interv Radiol. 2003;14(7): 827-831. https://doi.org/ 10.1097/01.RVI. 0000074375.49514.E3
6. Cotten A, Boutry N, Cortet B, et al. Percutaneous vertebroplasty: state of the art. Radiographics. 1998;18(2):311-320. https:// doi.org/10.1148/radiographics.18.2.9548581
7. Hulme PA, Krebs J, Ferguson SJ, et al. Vertebroplasty and kyphoplasty for vertebral compression fractures: a systematic review of randomized controlled trials. Spine. 2006;31(17): 1983-1991. https://doi.org/10.1097/01.brs. 0000224703.81888.07
8. Nguyễn Duy Thắng. Nghiên cứu tạo hình đốt sống qua da điều trị xẹp thân đốt sống cấp. Luận văn Thạc sĩ Y học, Đại học Y Hà Nội, 2014.
9. Phạm Mạnh Cường, Phạm Minh Thông. Ứng dụng tạo hình đốt sống qua da trong điều trị gãy xẹp thân đốt sống. Tạp chí Y học Việt Nam. 2008; X(2): 123-129.
10. Neer RM, Arnaud CD, Zanchetta JR, et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001;344(19): 1434-1441. https://doi.org/10. 1056/NEJM200105103441901