KHẢO SÁT NỒNG ĐỘ TSH, FT3, FT4 VÀ TỈ LỆ ĐÁI THÁO ĐƯỜNG, TIỀN ĐÁI THÁO ĐƯỜNG TÍP 2 Ở NGƯỜI TỪ 30-49 TUỔI

Abstract

Background: Many previous studies have demonstrated a correlation between type 2 diabetes mellitus and the development of thyroid disorders. Prediabetes is known as the transitional phase between normal blood glucose levels and diabetes. However, the association between prediabetes and thyroid function is unclear. This study aims to survey the association between TSH, FT4, and FT3 concentrations and the prevalence of prediabetes and type 2 diabetes in adults aged from 30 to 49 years old. Method: A cross-sectional study of 438 adults aged 30–49 years old who visit health check-ups at LeVanThinh Hospital from January to May in 2024.  Their blood samples were tested for fasting blood glucose, HbA1c, TSH, FT4, and FT3. Data on age and gender were also collected.  The results were stored and   analyzed   using   STATA   software. P-value of less than 0.05 was taken to be statistically significant. Results:  the majority was women and those aged 40 years and older. The prevalence of diabetes and prediabetes was low, 8.9% and 30.4%, respectively. The prevalence of thyroid abnormalities was approximately 15%. The mean fasting blood glucose and HbA1c levels were within the normal range. The median of TSH, FT3, and FT4 levels were within the reference range. When analyzing the concentrations of TSH, FT3, and FT4 in the pre-diabetes, diabetes and normal groups, the results showed that there was no statistically significant difference in TSH concentrations in the surveyed groups. However, for FT3 and FT4 concentrations, the study found a difference statistically in the surveyed groups with p=0.01. Conclusion: In this study, FT3 and FT4 concentrations were different in the pre-diabetes, diabetes and normal groups.