CLINICAL, SUBCLINICAL CHARACTERISTICS AND PREVALENCE OF PERIANAL LESIONS IN PATIENTS WITH CROHN’S DISEASE

Uyên Vũ Tú, Hồng Nguyễn Thị Vân, Hậu Vũ Hải

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Abstract

Objectives: To investigate the clinical, paraclinical characteristics and prevalence of perianal lesions in patients with Crohn’s disease. Subjects and Methods: A cross-sectional descriptive study was conducted on 140 patients treated at Bach Mai Hospital and Hanoi Medical University Hospital from August 2024 to May 2025. Result: The average age of the study was 31,66, with 51.1% being male. The main clinical symptoms of Crohn’s Disease were abdominal pain, digestive disorders and bloody stools. According to the Montreal classification, Crohn's  disease  was  most often  occurring  in the ilecolon and colon, rarely in the upper gastrointestinal tract. The prevalence of perianal lesions was 42,9%. Perianal fistula (78,3%) and abscess (50%) were the most common perianal lesions. Male sex, age < 40 years were significantly associated with a high prevalence of perianal lesions, whereas ileocolonic disease location and stricturing behavior were significantly associated with low prevalence of perianal lesions. Conclusions: Crohn's disease presents with a wide range of clinical manifestations. Perianal lesions are exceedingly common in patients with Crohn’s disease. Up to 50% of patients with perianal involvement have undergone surgery due to this complication. Young age, male sex, disease location and behaviour were significantly associated with the prevalence of perianal lesions.

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References

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