Article Sidebar
Views pdf: 64
CLINICAL AND LABORATORY CHARACTERISTICS AND ASSOCIATED FACTORS OF SUBOPTIMAL GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES AT VO TRUONG TOAN UNIVERSITY HOSPITAL IN 2025
Main Article Content
Abstract
Background: Diabetes mellitus is a rapidly increasing non-communicable disease. Understanding clinical and laboratory characteristics and factors influencing glycemic control in Vietnamese patients with type 2 diabetes (T2DM) is crucial. Objective: To investigate clinical and laboratory characteristics and identify associated factors of glycemic control in patients with type 2 diabetes mellitus. Materials and methods: A descriptive cross-sectional study with analytical components was conducted on 200 patients diagnosed with type 2 diabetes at Vo Truong Toan University Hospital from April 2025 to June 2025. Results: The median age of patients was 61 (IQR 53-67) years, with females representing approximately two-thirds of the participants. Median BMI was high at 26.89 kg/m². Regarding lifestyle factors, about one-third were smokers, one-third consumed alcohol, and the majority were physically inactive (97.0%). Concerning medical history, all patients had dyslipidemia, and a high proportion had hypertension (89.5%). Most patients had diabetes duration of ≥10 years (78.5%). Among the 200 patients, polyuria and polydipsia were the most common clinical symptoms (both 97.5%). Overweight/obesity (88.0%) and increased waist circumference (87.5%) were the most frequent clinical signs. Laboratory findings revealed a median HbA1C levels at 7.1% (IQR 6.5-8.4%), while median fasting blood glucose was within normal ranges at 8.35 mmol/L. Lipid profiles showed values within the high-normal range. Sedentary lifestyle, obesity, and increased waist circumference were significantly associated with suboptimal glycemic control (p<0.05). Conclusion: Patients with type 2 diabetes commonly presented with symptoms such as polyuria, polydipsia, overweight/obesity, and increased waist circumference, accompanied by comorbidities such as dyslipidemia and hypertension. Glycemic control rates remained suboptimal, with sedentary lifestyle, obesity, and increased waist circumference identified as significant factors influencing poor glycemic control.
Article Details
Keywords
type 2 diabetes mellitus, clinical characteristics, laboratory characteristics, glycemic control, associated factors
References
2. American Diabetes Association Professional Practice Committee (2022), "Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022", Diabetes Care, 45(Suppl 1), pp. S17-S38.
3. Hossain M. J., Al-Mamun M., Islam M. R. (2024), "Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused", Health Sci Rep, 7(3), pp. e2004.
4. Huynh G., Tran T. T., Do T. H. T., et al (2021), "Diabetes-Related Distress Among People with Type 2 Diabetes in Ho Chi Minh City, Vietnam: Prevalence and Associated Factors", Diabetes Metab Syndr Obes, 14, pp. 683-690.
5. International Diabetes Federation (2022), IDF Diabetes Atlas 2021, 10th Edition, The International Diabetes Federation, Brussels, Belgium.
6. Li S., Wang Y., Ying Y., et al (2023), "Independent and Joint Associations of BMI and Waist Circumference With the Onset of Type 2 Diabetes Mellitus in Chinese Adults: Prospective Data Linkage Study", JMIR Public Health Surveill, 9, pp. e39459.
7. Nguyen V. B., Thi K. H. P., Nguyen T. X., et al (2022), "Diabetes self-management and its associated factors among patients with diabetes in central Vietnam: A cross-sectional study", PLoS One, 17(7), pp. e0270901.
8. Ruangchaisiwawet A., Bankhum N., Tanasombatkul K., et al (2023), "Prevalence and the association between clinical factors and Diabetes-Related Distress (DRD) with poor glycemic control in patients with type 2 diabetes: A Northern Thai cross-sectional study", PLoS One, 18(11), pp. e0294810.