NGHIÊN CỨU TỶ LỆ THAI PHỤ NHIỄM LIÊN CẦU KHUẨN NHÓM B, ĐẶC ĐIỂM KHÁNG SINH ĐỒ VÀ MỘT SỐ YẾU TỐ LIÊN QUAN TẠI BỆNH VIỆN ĐA KHOA QUỐC TẾ VINMEC PHÚ QUỐC

Abstract

Objective: Determining the prevalence of Group B Streptococcus (GBS) in pregnant women, describe the antibiotic susceptibility profile, and identify associated risk factors of GBS strains isolated at Vinmec Phu Quoc International Hospital. Subjects and Methods: A descriptive cross-sectional study was conducted at Vinmec Phu Quoc from May 2024 to May 2025. A total of 522 pregnant women at 35–37 weeks of gestation were screened for GBS by vaginal-rectal swab cultures. GBS identification and antibiotic susceptibility testing were performed according to CLSI 2024 standards. Results: The rate of GBS infection was 28,2%. Isolated GBS strains were 100% sensitive to Ampicillin, Vancomycin, Linezolid, and Tigecycline; only 17,7% were sensitive to Clindamycin and 20,4% to Tetracycline. Significant associated risk factors included gestational diabetes mellitus (OR=3,03), history of preterm birth (OR=3,45), and history of abortion (OR=2,23). Maternal age, history of miscarriage, current vaginitis, and pyuria were not statistically significant. Conclusion: The prevalence of GBS pregnant women at Vinmec Phu Quoc is relatively high. Ampicillin remains the optimal treatment; however, individualized antibiotic susceptibility testing is recommended in cases of allergy or treatment failure. Routine GBS screening is essential, especially for high-risk pregnant women.