HIỆU QUẢ ĐIỀU TRỊ BỆNH HẠT CƠM QUANH MÓNG VÀ DƯỚI MÓNG BẰNG DUNG DỊCH KẼM SULPHAT 10%

Abstract

Objectives: To evaluate the efficacy of 10% zinc sulfate solution in the treatment of periungual and subungual warts. Subjects and Methods: A controlled comparative interventional study was conducted on 84 patients diagnosed with periungual and subungual warts at the National Dermatology Hospital from September 2024 to August 2025. Patients were randomly assigned into two groups: Group 1 received topical treatment with 10% zinc sulphate solution, while Group 2 received topical treatment with 5% imiquimod cream for 16 weeks. Patients were evaluated at baseline and every 4 weeks throughout the 16-week treatment period. Results: After 16 weeks of treatment, the proportion of patients achieving a “good” response in the zinc sulfate group was 42.9%, comparable to that in the 5% Imiquimod group (40.5%), with no statistically significant difference between the two groups (p > 0.05).Patient satisfaction was high (88.1%), and adverse effects were mild, mainly transient itching (2.4%). The cost of treatment with zinc sulphate solution was significantly lower than that of imiquimod (p < 0.01). Conclusion: 10% zinc sulfate solution is an effective, safe, and easily applicable treatment for periungual and subungual warts.