KHẢO SÁT TÌNH TRẠNG GAN NHIỄM MỠ KHÔNG DO RƯỢU (NAFLD) Ở NGƯỜI BỆNH ĐÁI THÁO ĐƯỜNG TÍP 2 BẰNG CHỈ SỐ FLI TẠI BỆNH VIỆN

Abstract

Introduction: Nonalcoholic fatty liver disease (NAFLD) is currently the leading cause of chronic liver disease worldwide and is increasingly recognized as a major public health burden. The prevalence of NAFLD is particularly high among patients with type 2 diabetes mellitus, playing a key role in the progression of both hepatic and cardiovascular complications. Objective: To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) using the Fatty Liver Index (FLI) and evaluate associated factors in patients with type 2 diabetes mellitus (T2DM) at Bach Mai Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 159 patients with T2DM at the Department of Endocrinology – Diabetes and the Endocrinology Outpatient Clinic of Bach Mai Hospital from October 2024 to June 2025. All patients underwent FLI assessment and abdominal ultrasound to detect hepatic steatosis. Results: Among 159 patients, 38 (23.9%) had a high risk of NAFLD (FLI > 60). The mean FLI in all patients was 39.63 ± 23.76, and 74.45 ± 9.81 in the NAFLD group. FLI showed significant positive correlations with BMI, waist circumference, GGT, and triglycerides (p < 0.05). No significant correlations were found between FLI and fasting plasma glucose, HbA1c, AST, ALT, total cholesterol, HDL-C, or LDL-C (p > 0.05). Conclusion: The prevalence of NAFLD in T2DM patients was relatively high. FLI, in combination with abdominal ultrasound, is a valuable tool for early screening and timely intervention to reduce complications.